PMID: 489149Mar 1, 1979Paper

Computer simulation as a tool for clinical trial design

International Journal of Bio-medical Computing
D R Jones

Abstract

Use of a computer simulation technique as a tool for optimising the design of a clinical trial is described. One of several aspects of trial design facilitated by use of the technique is the estimation of the number of patients required in the trial. The simulation tool provides the basis for structured and disciplined discussion of all the issues to be considered in designing a trial. Copies of the simulation program are available from the author.

References

May 21, 1977·British Medical Journal
Feb 1, 1971·The British Journal of Radiology·J W BoagE W Emery
Oct 1, 1971·The British Journal of Radiology·J L Haybittle
Mar 28, 1966·JAMA : the Journal of the American Medical Association·S Schor, I Karten

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Citations

Jun 3, 2000·Annual Review of Pharmacology and Toxicology·N H HolfordC C Peck
Mar 27, 2001·Annual Review of Pharmacology and Toxicology·P L Chan, N H Holford
Dec 25, 2008·Expert Review of Medical Devices·Mike S McGrathMichael A Mont
Apr 14, 2004·Journal of Internal Medicine·D Machin
Jan 1, 1988·The American Journal of Sports Medicine·H D Covvey

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