PMID: 8945856Sep 1, 1996Paper

Computer-supported analysis of continuous ambulatory manometric recordings in the human small bowel

Medical & Biological Engineering & Computing
A AndrioliJ Janssens

Abstract

An algorithm has been developed for the offline analysis of prolonged manometric recordings in the upper small intestine of humans. Sample data are acquired in the human duodenum and jejunum six solid-state strain-gauge transducers mounted on a silicon catheter that is connected to a portable digital recording device. The data are sampled at 4 Hz and filtered. For accurate calculations, the filtered signals are converted to cubic B-spline functions of order four. Based on an exponential weighted moving average, a base-line is calculated from the signal. Contractions are recognised on the basis of thresholds for minimum amplitude and duration. The developed algorithm calculates properties of these contractions, such as amplitude, duration, area and a motility index. In addition, the program automatically recognises normal motor patterns of the fasted human small intestine, such as the migrating motor complex, and aids in the identification of the postprandial motor pattern. Motor patterns are defined in terms of properties such as contraction frequency and propagation. In a validation procedure using conventional manual analysis, the program correctly identifies the number of individual contractions with a 98% confidence interva...Continue Reading

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Citations

Aug 30, 2000·Medical Engineering & Physics·J L Martinez-de-JuanJ L Ponce
Sep 22, 2012·American Journal of Physiology. Gastrointestinal and Liver Physiology·Pavlo L KovalenkoMarc D Basson
Feb 13, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·D AngJ Tack
May 17, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·B GeeraertsJ Tack
Mar 16, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A PapathanasopoulosJ Tack
Apr 10, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·T VanuytselJ Tack
Nov 14, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E DelooseJ Tack
Feb 25, 2006·Scandinavian Journal of Gastroenterology·Robespierre SantosJohn E Kellow
Apr 11, 2017·Journal of Pharmaceutical Sciences·Jens Van Den AbeelePatrick Augustijns
Apr 7, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·K J LeeJ Tack
Jan 29, 2016·The American Journal of Clinical Nutrition·Eveline DelooseJan Tack
May 3, 2018·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·D AngJ Tack
Aug 7, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E DelooseJ Tack
Mar 25, 2005·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·G H KoekJ Tack
Feb 25, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·M di StefanoJ Tack
Jan 6, 2006·Alimentary Pharmacology & Therapeutics·J TackJ Janssens
Feb 12, 2004·Alimentary Pharmacology & Therapeutics·K-J LeeJ Tack
May 23, 2003·American Journal of Physiology. Gastrointestinal and Liver Physiology·Kwang-Jae LeeJan Tack

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