Computerised analysis of standardised ultrasonographic images to monitor the repair of surgically created core lesions in equine superficial digital flexor tendons following treatment with intratendinous platelet rich plasma or placebo

The Veterinary Journal
G BoschH T M van Schie

Abstract

The effectiveness of new therapies to treat tendon injuries is difficult to determine and is often based on semi-quantitative methods, such as grey level analysis of ultrasonographic images or subjective pain scores. The alternatives are costly and long-lasting end-stage studies using experimental animals. In this study, a method of ultrasonographic tissue characterisation (UTC), using mathematical analysis of contiguous transverse ultrasonographic images, was used for intra-vital monitoring of the healing trajectory of standardised tendon lesions treated with platelet rich plasma (PRP) or placebo. Using UTC it was possible to detect significant differences between the groups in the various phases of repair. At end stage, over 80% of pixels showed correct alignment in the PRP group, compared with just over 60% in the placebo group (P<0.05). UTC also showed significant differences in the course of the healing process between PRP treated and placebo treated animals throughout the experiment. It was concluded that computerised analysis of ultrasonographic images is an excellent tool for objective longitudinal monitoring of the effects of treatments for superficial digital flexor tendon lesions in horses.

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Citations

Jan 30, 2014·American Journal of Veterinary Research·Alicia L BertoneRon L Genovese
Aug 29, 2012·American Journal of Veterinary Research·Stuart A VallanceLarry D Galuppo
Jan 29, 2013·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Nikolas BakshJohn G Kennedy
Jun 23, 2012·The Journal of Hand Surgery·Daisuke SatoToshihiko Ogino
Mar 16, 2011·PM & R : the Journal of Injury, Function, and Rehabilitation·Rosalyn T NguyenKelly McInnis
Mar 2, 2013·Equine Veterinary Journal·J A CadbyH T M van Schie
Sep 23, 2016·Frontiers in Veterinary Science·Nathaniel A White, Jennifer G Barrett
Nov 12, 2015·BMC Musculoskeletal Disorders·Andrea M Y WongJames E Gaida
Oct 4, 2012·The Journal of Bone and Joint Surgery. American Volume·Taralyn M McCarrelLisa A Fortier
Feb 17, 2017·Aesthetic Surgery Journal·Russell S FrautschiJames E Zins
Apr 20, 2021·Frontiers in Veterinary Science·Livia Camargo GarbinJorge U Carmona

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