Computerized acoustic cardiographic electromechanical activation time correlates with invasive and echocardiographic parameters of left ventricular contractility

Journal of Cardiac Failure
Stilianos Efstratiadis, Andrew D Michaels

Abstract

Electromechanical activation time (EMAT) is a systolic time interval defined as the time from Q-wave onset to the peak first heart sound. We assessed the correlation between systolic dysfunction and EMAT calculated using computerized acoustic cardiography. A total of 25 patients with heart failure contemporaneously underwent echocardiography, left-sided heart catheterization, and acoustic cardiography. Invasive pressure-volume hemodynamics included peak isovolumetric left ventricular (LV) pressure at the end-diastolic volume, end-diastolic pressure, dyssynchrony, and maximal +dP/dT. An EMAT/(R to R interval) (%EMAT) interval >or= 0.15 was prospectively defined as abnormal. An abnormal %EMAT correlated with a lower LV ejection fraction (50.9% +/- 18.6% with normal EMAT vs 32.0% +/- 10.9% with abnormal EMAT, P = .015), end-systolic elastance (3.07 +/- 1.56 mm Hg/mL vs 1.43 +/- 0.83 mm Hg/mL, P = .018), and peak isovolumetric LV pressure at the end-diastolic volume (317 +/- 90 mm Hg vs 222 +/- 67 mm Hg, P = .015). An abnormal %EMAT was associated with a higher end-systolic volume index (33.6 +/- 29.3 mL/m(2) vs 71.0 +/- 35.8 mL/m(2), P = .011), end-diastolic volume index (61.2 +/- 29.8 mL/m(2) vs 100.3 +/- 40.8 mL/m(2), P = .012),...Continue Reading

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Citations

Jan 20, 2011·Acute Cardiac Care·Shadi Karebsheh, Andrew D Michaels
Dec 21, 2012·Pacing and Clinical Electrophysiology : PACE·Krzysztof Z SiejkoMaria-Teresa Olivari
Sep 29, 2011·European Journal of Clinical Investigation·Naira RadzievskyYoram Agmon
Dec 11, 2014·IEEE Transactions on Bio-medical Engineering·Jonathan HerzigNathan Intrator
Mar 30, 2012·International Journal of Cardiology·Shang WangCheuk-Man Yu
Feb 18, 2014·International Journal of Cardiology·Yong-Na WenCheuk-Man Yu
Jun 21, 2016·International Journal of Cardiology·Shang WangCheuk Man Yu
Nov 16, 2017·Scientific Reports·Chin-Yu LinShih-Ann Chen
Mar 23, 2019·Pacing and Clinical Electrophysiology : PACE·Rohit WaliaHsuan-Ming Tsao
Jun 6, 2020·International Journal of Clinical Practice·Imen TrabelsiUNKNOWN GREAT Network
Nov 30, 2019·Disease Markers·Hui-Ju TsaiHung-Chun Chen
Nov 21, 2017·ESC Heart Failure·Pramodsingh H ThakurRoy S Gardner
Jan 7, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Leonardo CalòAntonio D'Onofrio
Sep 7, 2021·Clinical Cardiology·Fu Wei ZhangHai Rong Liang

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