PMID: 7333829Dec 1, 1981Paper

Computerized cranial tomography in Wilson disease: report of a case before and after penicillamine therapy

Italian Journal of Neurological Sciences
G LanziA Ottolini

Abstract

A patient with Wilson Disease presenting neurologic signs was treated with d-Penicillamine. Computerized cranial tomography (CT) performed before therapy showed symmetrical areas of low density in the region of the basal ganglia, enlargement of ventricles and bilateral increased density of the medial nuclei of the thalamus. This abnormality of the thalamus had not been reported previously in Wilson disease. After two years therapy there was an evident clinical improvement and at the same time a reduction of CT abnormalities. The reports on CT scanning in Wilson disease are reviewed.

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