PMID: 640925Apr 1, 1978Paper

Computerized measurement of pulmonary conductance and elastic recoil

Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
H J ColebatchC K Ng

Abstract

A system devloped for on-line measurement of transpulmonary pressure, gas flow at the mouth, change in expired volume and plethysmograph volume uses a minicomputer to control a multiplexed analog to digital converter. The computer identified samples as static or dynamic values by monitoring a voltage activating a solenoid valve, used to close the airway. Analysis of these samples by other task-specific programs yielded the static deflation pressure-volume (PV) curve, the conductance-recoil pressure, GL-Pst(L), relationship and the maximum expiratory flow-volume (MEFV) curve; the MEF-Pst(L) curve and conductance upstream from the equal pressure point were derived. The PV relationship was represented by a fourth-order polynomial and the GL-Pst(L) relationship by linear regression. In 11 subjects the results obtained using on-line data collection, compared with manual analysis of oscillograph recordings, showed small differences in static compliance and in the maximum Pst(L); but overall the two methods showed excellent agreement. Besides advantages of speed and objectivity, this system facilitates a more rigorous analytical treatment of elastic recoil and conductance.

Citations

Aug 1, 1985·Australian and New Zealand Journal of Medicine·I A Greaves, H J Colebatch
May 1, 1992·The Annals of Otology, Rhinology, and Laryngology·G A HarrisonA L Winkworth
Jul 20, 1987·The Medical Journal of Australia·D B Freiberg, H J Colebatch

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