PMID: 11926510Apr 3, 2002Paper

Computerized posturography with sway frequency analysis: application in occupational and environmental health

Industrial Health
Kazuhito YokoyamaHajime Sato

Abstract

To examine the effects of occupational and environmental neurotoxicants on vestibular, cerebellar and spinocerebellar functions, the following three groups of subjects were examined, using a computerized posturography with sway frequency analysis: (1) 49 male chemical factory workers exposed to lead stearate, aged 27-63 (mean 43) years, with concurrent blood lead concentrations (BPbs) of 11-113 (mean 48) microg/100 g and past mean BPbs of 7-52 (mean 24) microg/100 g; (2) 29 male sandal, shoe and leather factory workers, aged 35-73 (mean 51) years, with urinary 2,5-hexanedione (HD) concentrations of 0.41-3.06 (mean 1.20) mg/g creatinine; and (3) 9 females, aged 19-58 (mean 29) years, who were exposed to sarin accidentally 6-8 months before the study (Tokyo Subway Sarin Poisoning, March 20,1995) and showed plasma cholinesterase (ChE) activities of 13-95 (mean 68) IU/l on the day of poisoning. The pattern of posturographic changes in lead workers suggested that the vestibulocerebellum (lower vermis), anterior cerebellar lobe and spinocerebellar afferent pathway were asymptomatically affected; the vestibulocerebellar change reflected concurrent lead absorption and the anterior cerebellar one reflected past absorption. Similarly, ve...Continue Reading

Citations

May 7, 2011·Computer Methods in Biomechanics and Biomedical Engineering·Rigoberto Martinez-MendezToshiyo Tamura
Oct 20, 2004·Journal of Occupational Health·Noriko IshiiKatsuyuki Murata
Feb 14, 2006·Journal of Occupational and Environmental Medicine·Esko ToppilaPanu Oksa
Feb 7, 2018·International Journal of Occupational Safety and Ergonomics : JOSE·Concetto GiorgianniGiovanna Spatari
Feb 6, 2016·Journal of Occupational and Environmental Medicine·Kim SunwookThomas A Arcury

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