Concentration effects in the base-catalyzed hydrolysis of oligo(ethylene glycol)- and amine-containing methacrylic monomers

Designed Monomers and Polymers
Oleg A KazantsevMaria V Savinova

Abstract

Concentration effects in the base-catalyzed hydrolysis of water-soluble methacrylates (3-(N,N-dimethylaminoethyl) methacrylate (DMAEMA), 2-hydroxyethyl methacrylate (HEMA) and oligo(ethylene glycol) methacrylates (OEGMAs)) have been studied. These monomers are rapidly hydrolyzed in the presence of bases at the room temperature in dilute aqueous solutions, but the reaction rate decreases sharply in highly concentrated solutions. A clear correlation was found between a form of the viscosity isotherm for DMAEMA solutions and the concentration dependence of the autocatalytic hydrolysis rate which indicates the connection of process kinetics with the structure of solutions. These data should be considered when carrying out homo- and copolymerization of the previously mentioned monomers in aqueous solutions.

References

Nov 20, 1969·Biochemical and Biophysical Research Communications·C W BaldryJ Coombs
Mar 13, 1999·Journal of Biochemical and Biophysical Methods·K Sarmini, E Kenndler
May 1, 2012·International Journal of Polymeric Materials·Jonggu ParkJennifer S Laurence

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