Concentrations of leptin, adiponectin, and resistin in the serum of obese cats during weight loss

The Journal of Veterinary Medical Science
Satoshi TakashimaHitoshi Kitagawa

Abstract

We monitored changes in serum leptin, adiponectin, and resistin concentrations in obese cats during weight loss. Six naturally developed obese cats were fed low-fat, high-fiber dry food during a 9-week experimental period. Serum leptin, adiponectin, and resistin concentrations were measured at week 0, 4, 8, and 9. Body weight became significantly lower week 4 onward than that at week 0 (P<0.05 or 0.01). At week 9, serum leptin concentrations were significantly lower than those at week 0 (P<0.05). Contrarily, serum adiponectin and resistin concentrations did not significantly differ within the 9 weeks. While serum leptin levels were strongly positively correlated with body weight (r=0.923, P<0.001), serum adiponectin levels were moderately negatively correlated with it (r=-0.529, P<0.01), with serum resistin having a no correlation with body weight. Serum leptin levels might be more closely related with pathogenesis of adiposity than serum adiponectin or resistin in cats.

References

Dec 31, 2002·Biochemical and Biophysical Research Communications·Lisa PatelStephen A Smith
Mar 31, 2004·Journal of Internal Medicine·Claire M Steppan, Mitchell A Lazar
Jun 2, 2005·The Journal of Clinical Endocrinology and Metabolism·M GerberJ Kratzsch
Jun 15, 2006·The Journal of Nutrition·Alexander J German
Aug 12, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·M HoenigD C Ferguson
Oct 24, 2006·Endocrine Reviews·Maria E Trujillo, Philipp E Scherer
Oct 24, 2007·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·M A Lazar
Dec 21, 2007·Diabetes & Metabolism·B Antuna-PuenteJ-P Bastard
Mar 6, 2009·The Journal of Nutrition·Ricardo S VasconcellosAulus C Carciofi
Mar 6, 2009·The Journal of Veterinary Medical Science·Katsumi IshiokaMasayuki Saito
Apr 28, 2009·Veterinary Clinical Pathology·M Judith RadinBethany J Holycross
May 24, 2011·Journal of Obesity·Anis AmirhakimiGholamhosein Amirhakimi
Dec 20, 2011·Domestic Animal Endocrinology·A TvarijonaviciuteA J German
Nov 6, 2012·Veterinary Clinical Pathology·Emma M StrageInger Lilliehöök
Mar 14, 2013·Journal of Veterinary Internal Medicine·M Mazaki-ToviP A Schenck
Oct 8, 2013·European Journal of Internal Medicine·Goran LoncarVera Popovic
Nov 13, 2013·Journal of the American Animal Hospital Association·Dawn BrooksAngela Witzel
Dec 21, 2013·Journal of cardiology·Kazuto NakamuraKenneth Walsh
Aug 17, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Pilar Codoñer-Franch, Eulalia Alonso-Iglesias
Feb 14, 2018·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Joshua F BakerTamara B Harris

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Citations

Jan 7, 2021·Journal of Feline Medicine and Surgery·Audrey K Cook, Jeremy B Evans

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Methods Mentioned

BETA
ELISA

Software Mentioned

R
R Foundation for Statistical Computing

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