Concentrations of salinomycin in eggs and tissues of laying chickens fed medicated feed for 14 days followed by withdrawal for 3 days

Food Additives and Contaminants
A H AkhtarM A Shehata

Abstract

Laying chickens were fed medicated feed containing various concentrations of sodium salinomycin (SAL) for 14 days followed by a 3 day withdrawal period. Eggs, collected during treatment and withdrawal, tissues and ovarian yolk of birds slaughtered after 0, 1, and 3 days' withdrawal were extracted and analysed by high performance liquid chromatography (HPLC). Tissues, ovarian yolk and freeze-dried egg albumen and yolk were extracted with acetone, followed by partitioning with petroleum ether and HPLC analysis. Albumen was extracted with methanol and analysed without further clean-up. Salinomycin was detected at 520 nm after post-column reaction with vanillin at 95 degrees C. Recoveries of fortified salinomycin from freeze-dried eggs (albumen and yolk) and tissue, premix and feed were nearly quantitative (> 90%), except liver which was < 85%. The detection limit was estimated to be 5 ng g-1, with the practical quantifiable limit being about 10 ng g-1. Highest SAL concentrations were in the more fatty components such as egg yolk, ovarian yolk and subcutaneous fat. SAL residues in other tissues were generally low and followed the order liver, kidney, thigh and breast muscles. SAL residues were dependent on the SAL concentration in ...Continue Reading

References

Mar 1, 1979·Poultry Science·T T Migaki, W E Babcock
Jan 1, 1990·Scandinavian Journal of Psychology·T Gärling
Mar 1, 1993·Research in Veterinary Science·M AtefK Abo el-Sooud
Nov 1, 1995·Food Additives and Contaminants·G GerhardtH M Campbell

❮ Previous
Next ❯

Citations

Jun 7, 2012·Journal of Agricultural and Food Chemistry·Dorina BodiAngelika Preiss-Weigert
Dec 4, 2013·Food Chemistry·Małgorzata OlejnikPiotr Jedziniak
May 27, 2014·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Małgorzata OlejnikPiotr Jedziniak
Apr 29, 2006·Food Additives and Contaminants·Mervi Rokka, Kimmo Peltonen
Nov 13, 2004·Molecular Nutrition & Food Research·Mervi RokkaKimmo Peltonen
Jun 18, 2011·Journal of Veterinary Pharmacology and Therapeutics·V GoettingL A Tell
Apr 25, 2020·Journal of Food Science and Technology·Mararlene Ulberg PereiraBernardete Ferraz Spisso
Jun 24, 1998·The Veterinary Record·R K Hoop
Aug 6, 1998·Journal of Chromatography. a·R W Fedeniuk, P J Shand
Jan 16, 2001·Journal of Agricultural and Food Chemistry·C A Kan, M Petz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Agricultural and Food Chemistry
Leen MortierCarlos Van Peteghem
Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
V VandenbergeEls Daeseleire
© 2021 Meta ULC. All rights reserved