PMID: 7902037Nov 1, 1993

Concentric left ventricular hypertrophy in patients with Takayasu arteritis

Angiology
Y HashimotoF Numano

Abstract

Although aortic regurgitation (AR) in patients with Takayasu arteritis (TA) is believed to be caused by dilatation of the aortic ring or thickening of the aortic cusps, the pattern of left ventricular hypertrophy (LVH) in these patients has not been described. To clarify the geometry of the LV in patients with TA that had been documented both echocardiographically and hemodynamically, the authors evaluated 22 patients with TA and severe AR (group 1), 10 with TA and systemic hypertension (group 2), and 17 with isolated severe AR of other etiologies (group 3). M-mode echocardiography showed that LV dimensions were smaller in groups 1 and 2 than in group 3 and that wall thickness was greater in group 1 than in group 3. The concentric hypertrophic ratio (CHR = wall thickness/LV end-diastolic dimension+wall thickness) was larger than group 1 (p < 0.001) and group 2 (p < 0.01) than in group 3. CHR was similar in groups 1 and 2. Systolic blood pressure was significantly increased in group 2 and showed a tendency to increase in group 1 as compared with group 3. The results confirmed the presence of concentric LVH related to a pressure overload in patients with TA, even when TA was complicated by severe AR.

References

Jun 30, 2006·The International Journal of Cardiovascular Imaging·Senay Funda BiyikogluAli Sasmaz
Jan 26, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·JCS Joint Working Group
Apr 16, 1998·The Journal of Thoracic and Cardiovascular Surgery·Y TeradaK Okamura

Citations

Jan 1, 1977·American Heart Journal·E Lupi-HerreraJ E Vela
Jul 1, 1975·The Journal of Clinical Investigation·W GrossmanL P McLaurin
Apr 15, 1991·The American Journal of Cardiology·Y HashimotoH Maezawa
Sep 1, 1989·Circulation·R SubramanyanK G Balakrishnan
Oct 1, 1988·Journal of the American College of Cardiology·K Ishikawa
Feb 15, 1986·The American Journal of Cardiology·R B DevereuxN Reichek
Apr 1, 1987·Journal of the American College of Cardiology·G J PerryB Soto
Mar 1, 1984·The American Journal of Cardiology·S MorookaT Sugimoto

Related Concepts

Left Ventricular Structure
Diastolic Blood Pressure
Hypertensive Disease
Left Ventricular Hypertrophy
Aortic Valve Insufficiency
Aortitis Syndrome

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