PMID: 490200Sep 1, 1979Paper

Concept of neuron types in gustation in the rat

Journal of Neurophysiology
D C Woolston, R P Erickson

Abstract

1. In taste neurophysiology, from Pfaffmann's (49, 50) pioneering work until the present, the possibility of types of neurons corresponding in some sense with the "primary" taste qualities of Henning (33) has been entertained: recently types of gustatory neurons in peripheral nerves have been established according to which of the four classical stimuli is the "best stimulus." However, considerable variation occurs in the response profiles within neurons classified as belonging to the same type. The purpose of this research is to determine, using mathematical techniques where appropriate, if the within-type variation is spurious or, instead, indicates the absence of a typology of taste neurons. The data used were counts of the spike discharges of 50 individual taste neurons in the nucleus of the solitary tract of the rat, evoked by 32 diverse chemical stimuli. 2. Using as input the matrix of Pearson r correlation coefficients calculated for the responses of all pairings of neurons to all stimuli, multidimensional scaling analysis revealed a two-dimensional space in which no clear groupings of neurons occurred. 3. In a hierarchical cluster analysis of the neuron response profile similarities, no evidence of grouping was found, su...Continue Reading

Citations

Feb 17, 1997·The Journal of Comparative Neurology·D W PumplinD V Smith
Apr 9, 2008·The Behavioral and Brain Sciences·Robert P Erickson
Dec 18, 2004·Journal of Neurophysiology·Justus V VerhagenThomas R Scott
Jan 23, 2015·Journal of Neurophysiology·John-Paul BairdStuart A McCaughey
Feb 1, 1985·Pharmacology, Biochemistry, and Behavior·S S SchiffmanC Diaz
Dec 16, 1982·Brain Research·T C Pritchard, T R Scott
Sep 28, 1990·Science·T R Scott, B K Giza

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