PMID: 4905676Feb 1, 1970Paper

Concerning the influence of integrated episomes on chromosomal replication in Escherichia coli

Proceedings of the National Academy of Sciences of the United States of America
H Eberle

Abstract

Two strains of Escherichia coli K12, C600, and DG163, in which the origins and directions of DNA replication had been mapped previously, were made lysogenic for lambda and lambdai434. The origins of replication in these lysogenic strains were located with respect to the prophage location by chromosome alignment and subsequent hybridization of (3)H-labeled lambda vir DNA with newly replicated and "old" DNA. The results obtained are consistent with similar origins of replication observed in the nonlysogenic strains. These findings suggest that DNA replication in these cells is under the control of the E. coli chromosomal replicon and is independent of the presence of the lambda replicon as predicted by the Jacob, Brenner, and Cuzin model of DNA replication.

References

Nov 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·M Abe, J Tomizawa
Mar 28, 1968·Journal of Molecular Biology·B WolfD A Glaser
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·L G Caro, C M Berg
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·B WolfD A Glaser
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·W VielmetterA Schütte
Jan 1, 1969·Annual Review of Biochemistry·K G Lark
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·S Mousset, R Thomas
Sep 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·R RudnerE Chargaff
Jul 1, 1965·Journal of Molecular Biology·J L Rothman
Jun 13, 1966·Biochemical and Biophysical Research Communications·D T Denhardt
Apr 1, 1963·Proceedings of the National Academy of Sciences of the United States of America·T NAGATA
Feb 15, 1963·Proceedings of the National Academy of Sciences of the United States of America·E BURGI
Sep 1, 1963·Proceedings of the National Academy of Sciences of the United States of America·D B COWIE, B J MCCARTHY
Jun 1, 1960·Analytical Biochemistry·J D MANDELL, A D HERSHEY

❮ Previous
Next ❯

Citations

Jan 1, 1975·Molecular & General Genetics : MGG·R H PritchardJ Collins
Feb 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·J M Louarn, R E Bird
Jan 1, 1973·Progress in Biophysics and Molecular Biology·D W Smith
Jun 25, 1976·Journal of Molecular Biology·M ChandlerL Caro
Oct 14, 1972·Journal of Molecular Biology·R E BirdL Caro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.