Concise synthesis of isoquinoline via the Ugi and Heck reactions

Organic Letters
Zheng XiangZhen Yang

Abstract

[reaction: see text] Two types of isoquinoline scaffolds were successfully constructed in a combinatorial format via the Ugi four-component reaction and the Pd-catalyzed intramolecular Heck reaction, starting from readily available starting materials.

References

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Aug 14, 2003·Chemical Reviews·Amy B Dounay, Larry E Overman

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Citations

Jul 4, 2012·Proceedings of the National Academy of Sciences of the United States of America·Timothy J DonohoeJosé A Bassuto
Jun 9, 2005·Current Opinion in Chemical Biology·Agnieszka Ulaczyk-Lesanko, Dennis G Hall
Feb 6, 2015·Chemical Society Reviews·Upendra K SharmaErik V Van der Eycken
Nov 20, 2014·Organic & Biomolecular Chemistry·Wen-Tao WeiMing Yan
Mar 23, 2013·Organic & Biomolecular Chemistry·Hongliang LiuZhiyong Wang
Sep 25, 2007·Organic Letters·James D SunderhausStephen F Martin
Jun 30, 2021·The Journal of Organic Chemistry·Qian WangAlexander Dömling
Mar 24, 2015·The Journal of Organic Chemistry·Muhammad Shareef MayoMing Bao
May 6, 2015·The Journal of Organic Chemistry·Jean-Baptiste E Y RouchetChristophe Hoarau
Dec 11, 2013·The Journal of Organic Chemistry·Chao CheShuo Lin
Sep 12, 2006·Journal of Combinatorial Chemistry·Zhibo MaZhen Yang
Nov 15, 2005·Journal of Combinatorial Chemistry·Roland E Dolle
Jan 29, 2005·The Journal of Organic Chemistry·Miwako MoriYoshihiro Sato

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