Concomitant colitis associated with primary sclerosing cholangitis

Journal of Gastroenterology
Naohito UchidaShigeki Kuriyama

Abstract

Between 1985 and 2001, seven Japanese patients (four males and three females) were diagnosed as having primary sclerosing cholangitis (PSC) in our hospital. All seven patients received total colonoscopy with distal ileoscopy. All four male patients were diagnosed as having colitis by colonoscopy, while none of the three female patients had colitis. The four patients with colitis did not have any symptoms attributable to colitis, such as diarrhea or hematochezia. In three of the four patients, unclassified colitis was the most suitable diagnosis, because there were no typical findings of ulcerative colitis or Crohn's disease. The remaining patient was diagnosed as having eosinophilic colitis. By colonoscopic visualization, the right-sided colon, including the terminal ileum, was mainly involved, but the lesions were not severe. The main findings were redness, erosion, stenosis, and insufficiency of haustral formation. Histologically, these lesions were nonspecific inflammatory changes in the three patients with unclassified colitis. In the patient with eosinophilic colitis, remarkable infiltration of eosinophils was observed. Thus, unclassified colitis appeared to be the main complication in these patients with PSC. Males predom...Continue Reading

Citations

May 18, 2011·Journal of Crohn's & Colitis·Konstantinos H KatsanosEpameinondas V Tsianos
Feb 1, 2012·Clinical Journal of Gastroenterology·Kazuhiko NakamuraRyoichi Takayanagi
Aug 27, 2010·Journal of Hepato-biliary-pancreatic Sciences·Hitoshi SanoTakashi Joh
Oct 13, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hajime Takikawa
Aug 19, 2009·Internal Medicine·Katsuhiko HoriuchiToshio Fukusato
Oct 17, 2014·Internal Medicine·Naohiko GunjiHiromasa Ohira
Jun 29, 2018·Journal of Gastroenterology·Hiroyuki IsayamaUNKNOWN PSC guideline committee Members: Ministry of Health, Labour and Welfare (Japan) Research Project, The Intractable Hepatobili

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