Concomitant gastroparesis negatively affects children with functional gallbladder disease.

Journal of Pediatric Gastroenterology and Nutrition
Bruno P ChumpitaziRobert J Shulman

Abstract

The aim of the present study was to determine whether concomitant gastroparesis and biliary dyskinesia (BD) occur in children, and if so, to determine whether concomitant gastroparesis affects clinical outcome in children with BD. We conducted a retrospective chart review of children with BD (ejection fraction <35% on cholescintigraphy, with no other metabolic or structural cause) who completed a solid-phase gastric emptying scintigraphy scan within 12 months of abnormal cholescintigraphy. Children were classified into 1 of 4 clinical outcome groups (excellent, good, fair, poor). Thirty-five children with a mean follow-up time of 23.1±17.3 (standard deviation) months were included. Twenty (57%) children were identified as having concomitant gastroparesis (GP) with BD. Children with concomitant GP were more likely to have a poor clinical outcome compared with those with BD alone (P<0.005). In children undergoing cholecystectomy, those with concomitant GP were more likely to have a fair or poor clinical outcome compared with those with BD alone (P<0.01). Factors predicting a more favorable clinical outcome were having BD alone and not having limitations in activity (eg, school absences) at the time of presentation. Concomitant GP...Continue Reading

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Citations

Apr 10, 2014·Digestive Diseases and Sciences·Arvind I SrinathKlaus Bielefeldt
Mar 5, 2013·Digestive Diseases and Sciences·Henry P ParkmanFrank Hamilton
Apr 11, 2014·Pediatric Annals·Arvind SrinathKlaus Bielefeldt
Dec 17, 2015·Journal of Pediatric Gastroenterology and Nutrition·Patrick M JonesWilliam E Bennett
Dec 20, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Katja KovacicMiguel Saps

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