Concomitant Mitral Regurgitation in Patients With Chronic Aortic Regurgitation.

Journal of the American College of Cardiology
Li-Tan YangHector I Michelena

Abstract

Etiology, mechanisms, and survival of mitral regurgitation (MR) plus hemodynamically-significant chronic aortic regurgitation (AR) are mostly unknown. The purpose of this study was to investigate the prevalence, mechanisms, etiologies, and survival impact of coexistent ≥ moderate MR in AR patients. Consecutive patients with ≥ moderate-severe AR were retrospectively identified between 2004 and 2019. Of 1,239 eligible patients (61 ± 18 years, 80% men), 1,072 (86%) had pure AR, and 167 (14%) had AR + MR (9% functional mitral regurgitation [FMR] [84% nonischemic] and 5% organic mitral regurgitation [OMR] [62% degenerative]). At baseline transthoracic echocardiogram, pure AR versus AR + OMR versus AR + FMR exhibited differences in age (59 ± 18, 62 ± 16, and 73 ± 14 years, respectively), female sex (18%, 27%, and 39%, respectively), symptoms (36%, 41%, and 64%, respectively), atrial fibrillation (5%, 17%, and 36%, respectively), left ventricular (LV) ejection fraction (59%, 58%, and 46%, respectively), LV end-systolic dimension and volume index, ≥ moderate tricuspid regurgitation (TR) (7%, 35%, and 53%, respectively), and right ventricular systolic pressure (32 ± 11, 45 ± 15, and 50 ± 14 mm Hg, respectively), all p < 0.0001. After a ...Continue Reading

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Jan 11, 2020·Journal of the American College of Cardiology·Li-Tan YangHector I Michelena
Feb 1, 2020·Journal of the American College of Cardiology·Ons MarsitJonathan Beaudoin

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Citations

Feb 10, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Kinjal M PatelSandeep Krishnan
Jul 18, 2020·Journal of the American College of Cardiology·Christophe TribouilloyPhilippe Unger
Aug 29, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alec VahanianUNKNOWN ESC/EACTS Scientific Document Group
Aug 29, 2021·European Heart Journal·Alec VahanianUNKNOWN ESC Scientific Document Group
Oct 31, 2020·Journal of the American College of Cardiology·Xuan JiangTianxiang Gu
Oct 31, 2020·Journal of the American College of Cardiology·Li-Tan YangHector I Michelena

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