PMID: 20625656Jul 14, 2010Paper

Concomitant thyroid Malt lymphoma and papillary thyroid carcinoma

Arquivos brasileiros de endocrinologia e metabologia
Giulianno Molina de MeloRicardo Antenor de Souza E Souza

Abstract

The objective of this study was to describe the rare thyroid MALT lymphoma concomitant with papillary thyroid carcinoma in a male patient who was submitted to total thyroidectomy. Treatment and follow-up issues are addressed. Male patient complains of fast thyroid enlargement without lymphadenophaty and normal clinical exams. Total thyroidectomy was indicated and performed without any complications. The pathology showed multicentric papillary thyroid carcinoma, concomitant thyroid MALT lymphoma and Hashimoto's thyroiditis. The immunohistochemistry assay was positive for CD 20, CD 43, CD 79, AE1/AE3. The staging studies showed no evidence of both metastasis, Ann Harbor stage IE, without B symptoms. After RIT no further radiotherapy or chemotherapy was indicated. Nowadays the thyroglobulin is undetectable, without recurrences at two years of follow-up. It was concluded that primary thyroid MALT lymphoma is uncommon being the papillary thyroid carcinoma more frequent. Both occurring concomitantly is very rare and the treatment has to prioritize the tumor of worst prognosis at the discovery moment.

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Citations

Jun 11, 2011·Pathology Research International·Triantafyllia KoletsaIoannis Kostopoulos
Aug 30, 2016·Asian Pacific Journal of Tropical Medicine·Saul Levy-BlitchteinJuana Del Valle Mendoza
Feb 8, 2018·Archives of Endocrinology and Metabolism·Maria TrovatoAlfredo Campennì
May 10, 2012·Thyroid : Official Journal of the American Thyroid Association·Vicky ChengChristian Nasr
Jul 13, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Evangeline VassilatouGeorge Dimitriadis
Oct 19, 2011·Case Reports in Medicine·Emiliano SordiPrisco Piscitelli
Dec 30, 2016·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Qiong WuBo Zhang
Jan 8, 2021·BMJ Case Reports·Joshua AgilinkoMuhammad Shakeel
Feb 20, 2020·European Thyroid Journal·Evangelos KarvounisEva Kassi

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