Concordance assessment of self-reported medication use in the Netherlands three-generation Lifelines Cohort study with the pharmacy database iaDB.nl: The PharmLines initiative

Clinical Epidemiology
Rahmat SediqEelko Hak

Abstract

While self-reported data are commonly used as a source of medication use for pharmaco-epidemiological studies, such information is prone to forms of bias. Several previous studies showed that various factors like age, type of drug and data collection method may influence accuracy. We aimed to assess the concordance of the self-reported medication use that was documented at entry to the Lifelines Cohort Study, a three-generation follow-up study in the Netherlands that started in 2006 and included over 167,000 participants. As part of the PharmLines Initiative, we collected medication data from the Lifelines participants encoded according to the Anatomical Therapeutic Chemical (ATC) coding scheme and linked the data via Statistics Netherlands to the widely used and representative pharmacy prescription database of the University of Groningen, IADB.nl. Analyses were conducted at second level of ATC coding for all recorded medications as well as a top list of most used medications at drug-specific fifth level. Cohen's kappa statistics were used to measure the concordance for all participants according to sex and age. The level of concordance between the two data sources largely differed according to the therapeutic class. Medication...Continue Reading

Citations

May 23, 2020·Clinical and Translational Science·Noraly StamJurjen J Luykx
Jan 21, 2020·Journal of Parkinson's Disease·Lana M ChahineUNKNOWN behalf of the Fox Insight Study
Nov 26, 2020·PloS One·Hanneke J C M WoutersBruce H R Wolffenbuttel
Jan 12, 2021·Chronic Illness·Cristiano S MouraSasha Bernatsky
May 25, 2021·Research and Practice in Thrombosis and Haemostasis·Nicholyn SelvanayagamKerstin de Wit
Dec 7, 2021·Frontiers in Endocrinology·Rikke ViggersPeter Vestergaard
Dec 16, 2021·British Journal of Clinical Pharmacology·Nersi AlaeddinFolgerdiena M de Vries

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