PMID: 18200364Jan 18, 2008Paper

Concordance between clinical and pathological staging in patients with stages I or II non-small cell lung cancer subjected to surgical treatment

Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Pedro Augusto Reck Dos SantosJosé Antonio Lopes de Figueiredo Pinto

Abstract

To compare clinical and pathological staging in patients with non-small cell lung cancer submitted to surgical treatment, as well as to identify the causes of discordance. Data related to patients treated at the Department of Thoracic Surgery of the Pontifical Catholic University of Rio Grande do Sul São Lucas Hospital were analyzed retrospectively. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated for clinical stages IA, IB, and IIB. The kappa index was used to determine the concordance between clinical and pathological staging. Of the 92 patients studied, 33.7% were classified as clinical stage IA, 50% as IB, and 16.3% as IIB. The concordance between clinical and pathological staging was 67.5% for stage IA, 54.3% for IB, and 66.6% for IIB. The accuracy of the clinical staging was greater for stage IA, and a kappa of 0.74, in this case, confirmed a substantial association with pathological staging. The difficulty in evaluating nodal metastatic disease is responsible for the low concordance in patients with clinical stage IB. The concordance between clinical and pathological staging is low, and patients are frequently understaged (in the present study, only one case was...Continue Reading

References

Apr 25, 2000·Chest·J Deslauriers, J Grégoire
May 10, 2001·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F TanakaH Wada
Dec 13, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·H Hoffmann
Dec 7, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Erdogan CetinkayaVeysel Yilmaz
Sep 10, 2003·The Annals of Thoracic Surgery·Robert J CerfolioJames M Mountz
Jan 23, 2004·The New England Journal of Medicine·Alexander Spira, David S Ettinger
Mar 1, 2005·The Annals of Thoracic Surgery·Angel López-EncuentraUNKNOWN Bronchogenic Carcinoma Cooperative Group of the Spanish Society of Pneumology and Thoracic Surgery
Sep 27, 2005·The Annals of Thoracic Surgery·Robert James CerfolioMohammad Eloubeidi
Nov 25, 2005·The Annals of Thoracic Surgery·Alex G LittleAndrew K Stewart
Nov 25, 2005·The Annals of Thoracic Surgery·David Feller-KopmanArmin Ernst

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