Concordane of OSTA and lumbar spine BMD by DXA in identifying risk of osteoporosis

Journal of Orthopaedic Surgery and Research
ChunYan LuSongQuan Wei

Abstract

To investigate the accuracy of Osteoporosis Self-assessment Tool for Asians (OSTA) in identifying the risk of osteoporosis in postmenopausal women. To validate use of OSTA risk index by comparing it with the bone mineral density (BMD) of lumbar spine measured by dual energy X-ray absorptiometry (DXA). The data of lumbar spine BMD (LS BMD) measurements by DXA of 218 postmenopausal women of Han nationality in Sichuan province were compared with OSTA risk index. The concordance of OSTA and LS BMD were calculated and analyzed by fourfold table and receiver operating characteristic (ROC) curve. The prevalence of osteoporosis in these women was 40.4% and 61.5%, with the LS BMD T score cutoffs -2.5 and -2.0, respectively. The sensitivity, specificity, and accuracy of OSTA risk index compared with T score cutoff -2.5 of LS BMD were 59.1%, 56.9% and 57.8%, respectively, while they were 57.5%, 63.1%, 59.6% by T score cutoff -2.0. For identifying risk of osteoporosis, the concurrence was lower than those reported studies when comparing LS BMD measurements to OSTA risk index in Chinese Han nationality postmenopausal women of Sichuan province. Physicians should identify women who need BMD measurement according to more factors rather than ag...Continue Reading

References

Feb 1, 1995·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L J Melton
Oct 3, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L K KohUNKNOWN Osteoporosis Self-Assessment Tool for Asians (OSTA) Research Group
Aug 5, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Annie W C KungPhilip D Ross
Aug 26, 2003·Mayo Clinic Proceedings·Robert A AdlerValentina I Petkov
Sep 30, 2003·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·H M ParkUNKNOWN OSTA
Jan 2, 2004·QJM : Monthly Journal of the Association of Physicians·F RichyJ-Y Reginster
Jan 13, 2004·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Stephen F HodgsonUNKNOWN AACE Osteoporosis Task Force
Jan 20, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Suzanne M CadaretteSusan B Jaglal
Nov 9, 2006·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·UNKNOWN Chinese Association of Integrative Medicine, Liver Disease Committee

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Citations

Feb 2, 2012·QJM : Monthly Journal of the Association of Physicians·S S JamesonD J Deehan
Nov 16, 2017·International Journal of Environmental Research and Public Health·Cheng-Shyuan RauChing-Hua Hsieh

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Methods Mentioned

BETA
X-ray

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