Concordant and Discordant Cardiac Magnetic Resonance Imaging Delayed Hyperenhancement Patterns in Patients with Ischemic and Non-Ischemic Cardiomyopathy

Korean Circulation Journal
Eun Kyoung KimJae K Oh

Abstract

The diagnosis of ischemic (ICM) and non-ischemic cardiomyopathy (NICM) is conventionally determined by the presence or absence of coronary artery disease (CAD) in the setting of a reduced left systolic function. However the presence of CAD may not always indicate that the actual left ventricular (LV) dysfunction mechanism is ischemia, as other non-ischemic etiologies can be responsible. We investigated patterns of myocardial fibrosis using delayed hyperenhancement (DHE) on cardiac magnetic resonance (CMR) in ICM and NICM. Patients with systolic heart failure who underwent a CMR were prospectively analyzed. The heart failure diagnosis was based on the modified Framingham criteria and LVEF <35%. LV dysfunction was classified as ICM or NICM based on coronary anatomy. A total of 101 subjects were analyzed; 34 were classified as ICM and 67 as NICM. The DHE pattern was concordant with the conventional diagnosis in 27 (79.4%) of the patients with ICM and 62 (92.5%) of the patients with NCIM. A discordant NICM DHE pattern was present in 8.8% of patients with ICM, and an ICM pattern was detected 6.0% of the patients with NICM. Furthermore, 11.8% of the patients with ICM and 1.5% of those with NICM demonstrated a mixed pattern. A subset ...Continue Reading

References

Dec 1, 1986·Journal of the American College of Cardiology·E Braunwald, J D Rutherford
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Jan 15, 2002·Journal of the American College of Cardiology·G Michael FelkerChristopher M O'Connor
Jun 15, 2004·Journal of the American College of Cardiology·James C C MoonDudley J Pennell
Sep 22, 2007·Journal of Cardiovascular Medicine·Chiara CaloreSabino Iliceto
Jan 27, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Kristopher W CummingsPamela K Woodard
Feb 2, 2010·Journal of the American College of Cardiology·Han W KimRaymond J Kim

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Citations

Apr 14, 2017·The Korean Journal of Internal Medicine·Mi-Jeong Kim, Mi-Seung Shin
Jan 23, 2016·Korean Circulation Journal·Eui-Young Choi
Oct 19, 2019·Scandinavian Cardiovascular Journal : SCJ·Jason Leo WalshHussain Isma'eel

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

Argus

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