Concurrent acute Vogt-Koyanagi-Harada disease in one eye and chronic disease in the fellow eye

Journal of Ophthalmic Inflammation and Infection
Sana KhochtaliMoncef Khairallah

Abstract

Vogt-Koyanagi-Harada (VKH) disease is a granulomatous panuveitis, usually involving both eyes at the same time or within a few days or weeks. Acute and chronic diseases are characterized by distinct clinical features, treatment modalities, and visual outcomes. We report an atypical case of probable VKH disease, with features of acute disease in one eye and chronic disease in the fellow eye. A 53-year-old female presented with exudative retinal detachment associated with mild vitritis in the right eye and anterior uveitis, vitritis, and sunset-glow fundus in the left eye. Based on clinical findings and results of multimodal imaging including fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, indocyanine green angiography, and B-scan ultrasonography, a diagnosis of acute VKH disease in the right eye and chronic VKH disease in the left eye was made. The patient received systemic corticosteroids and mycophenolate mofetil. After a 15-month follow-up, the right fundus eye was normal, and there was a sunset-glow fundus in the left eye. VKH disease may begin with asymptomatic unilateral ocular involvement. The patient may present only when the fellow eye is affected. A significant delay before in...Continue Reading

References

Mar 15, 1991·American Journal of Ophthalmology·D J ForsterN A Rao
Nov 30, 2002·Japanese Journal of Ophthalmology·Noriko KoudaKazuyuki Sasaki
Mar 25, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yoshihiko UsuiNarsing A Rao
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Dec 29, 2009·Ophthalmology·Narsing A RaoRussell W Read
May 17, 2012·Journal of Ophthalmic Inflammation and Infection·Nikki Y Far, David T L Liu

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