Concurrent and predictive validity of components of disordered thinking in schizophrenia

Schizophrenia Bulletin
R A KnightC G Watson

Abstract

Although the various manifestations of disordered thought have played a central role in diagnostic and theoretical considerations of schizophrenia, such symptoms have not been found specific to schizophrenia, and at best have shown weak relations to outcome. As part of a 7-year followup study of a sample of young, acute, psychotic inpatients, we explored the hypothesis that despite these poor results there might be particular components of disordered thought that might have prognostic utility and be able to discriminate narrowly defined schizophrenics. Using extant symptom scales as our models, we constructed five internally consistent scales of disordered thought from behavioral ratings made using the Psychotic Inpatient Profile--Poverty of Speech, Attentional Impairment, Incoherence, Delusions, and Hallucinations. We tested the ability of these scales to predict various aspects of outcome adaptation including outcome diagnosis. In general, the Attentional Impairment scale demonstrated the best prognostic utility, predicting poorer outcome in several domains. Paradoxically, patients diagnosed by Research Diagnostic Criteria (RDC) as definite schizophrenic at outcome had been rated as showing less attentional impairment than pr...Continue Reading

Citations

Jan 1, 1989·European Archives of Psychiatry and Neurological Sciences·G Heim
Mar 1, 1992·Comprehensive Psychiatry·V PeraltaJ de Leon
Feb 8, 2018·The Kaohsiung Journal of Medical Sciences·Yong Chon ParkSeon-Cheol Park

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