Concurrent determination of alpha-tocopherol and free fatty acids in human plasma by glass open tubular capillary column gas chromatography.

Journal of Chromatography
S N Lin, E C Horning

Abstract

A new gas chromatographic procedure was developed for the concurrent analysis of mixtures of long-chain acids (as methyl esters), cholesterol (as the trimethylsilyl ether) and the tocopherols (as trimethylsilyl ethers). This method was used in a study of free fatty acids and alpha-tocopherol in the plasma of normal subjects and stroke patients. The chromatographic separation was based upon the use of thermostable glass open tubular capillary columns prepared with Silanox (procedure of Lin, Pfaffenberger and Horning) and a new polar liquid phase (Schwartz-Mathews polyphenyl ether sulfone phase). The German-Horning injection system was used in a modified gas chromatograph.

References

Sep 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·M Hamberg, B Samuelsson
Oct 25, 1974·Nature·M L RosenlundD Kritchevsky
Dec 18, 1972·Annals of the New York Academy of Sciences·B A UnderwoodM Navab
Feb 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·M HambergB Samuelsson
Nov 1, 1972·Journal of the American Oil Chemists' Society·A J SheppardW D Hubbard
Dec 18, 1972·Annals of the New York Academy of Sciences·A L Tappel
Jun 28, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·K FalholtW Falholt
Dec 27, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·M Carruthers, D A Young
Jul 1, 1973·Circulation·R E Olson
Jan 18, 1974·Science·C A RielyM Lieberman
Jan 30, 1974·Journal of Chromatography·H Ko, M E Royer
Jan 10, 1974·Prostaglandins·A L Willis
Mar 1, 1972·Journal of Agricultural and Food Chemistry·M K Govind Rao, E G Perkins
Nov 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·I MolenaarH A Polman
May 1, 1971·Analytical Biochemistry·S Kashket
Dec 9, 1965·The New England Journal of Medicine·H J BinderH M Spiro
Feb 1, 1956·The Journal of Clinical Investigation·V P DOLE
Jun 1, 1961·Proceedings of the Society for Experimental Biology and Medicine·P L HARRISJ L JENSEN
Oct 1, 1964·Proceedings of the Society for Experimental Biology and Medicine·J G BIERIE L ANDREWS

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Citations

Sep 19, 1998·Free Radical Biology & Medicine·M C PolidoriM F Beal
Sep 6, 2005·Free Radical Biology & Medicine·Antonio CherubiniPatrizia Mecocci
Oct 10, 1980·Journal of Chromatography·G Osterlöf, A Nyheim

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