Concurrent EEG- and fMRI-derived functional connectomes exhibit linked dynamics

BioRxiv : the Preprint Server for Biology
Jonathan WirsichSepideh Sadaghiani

Abstract

Connectivity across distributed brain regions commonly measured with functional Magnetic Resonance Imaging (fMRI) exhibits infraslow (<0.1Hz) spatial reconfigurations of potentially critical importance to cognition. Cognitively relevant neural communication, however, employs synchrony at fast speeds. It is unclear how fast oscillation-coupling across the whole-brain connectome relates to connectivity changes in fMRI, an indirect measure of neural activity. In two datasets, electroencephalography (EEG) revealed that synchronization in all canonical oscillation-bands reconfigures at infraslow speeds, coinciding with connectivity changes in concurrently recorded fMRI in corresponding region-pairs. The cross-modal tie of connectivity dynamics was widely distributed across the connectome irrespective of EEG frequency-band. However, the cross-modal tie was strongest in visual to somatomotor connections for slower EEG-bands, and in connections involving the Default Mode Network for faster EEG-bands. The findings provide evidence that functionally relevant neural synchrony in all oscillation-bands slowly reconfigures across the whole-brain connectome, and that fMRI can reliably measure such dynamics.

Related Concepts

Brain
Electroencephalography
Hemodynamics
Magnetic Resonance Imaging
Neurons
Imaging of Brain
A Band
Brain Injuries
FMRI
Patterns

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.