Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence

Journal of Neurophysiology
Huan LuoJonathan Z Simon

Abstract

A natural sound can be described by dynamic changes in envelope (amplitude) and carrier (frequency), corresponding to amplitude modulation (AM) and frequency modulation (FM), respectively. Although the neural responses to both AM and FM sounds are extensively studied in both animals and humans, it is uncertain how they are corepresented when changed simultaneously but independently, as is typical for ecologically natural signals. This study elucidates the neural coding of such sounds in human auditory cortex using magnetoencephalography (MEG). Using stimuli with both sinusoidal modulated envelope (f(AM), 37 Hz) and carrier frequency (f(FM), 0.3-8 Hz), it is demonstrated that AM and FM stimulus dynamics are corepresented in the neural code of human auditory cortex. The stimulus AM dynamics are represented neurally with AM encoding, by the auditory steady-state response (aSSR) at f(AM). For sounds with slowly changing carrier frequency (f(FM) <5 Hz), it is shown that the stimulus FM dynamics are tracked by the phase of the aSSR, demonstrating neural phase modulation (PM) encoding of the stimulus carrier frequency. For sounds with faster carrier frequency change (f(FM) > or = 5 Hz), it is shown that modulation encoding of stimulus...Continue Reading

References

Nov 1, 1979·The Journal of the Acoustical Society of America·N F Viemeister
Aug 1, 1990·Hearing Research·G B Henning, E Zwicker
Jul 1, 1987·The Journal of the Acoustical Society of America·T W PictonA C Maiste
Oct 13, 1995·Science·R V ShannonM Ekelid
Mar 1, 1995·The European Journal of Neuroscience·B H Gaese, J Ostwald
Feb 1, 1994·The Journal of the Acoustical Society of America·R DrullmanR Plomp
Oct 1, 1996·The Journal of the Acoustical Society of America·B C Moore, A Sek
May 12, 1998·Audiology & Neuro-otology·B Lütkenhöner, O Steinsträter
Apr 15, 1999·Annual Review of Neuroscience·A J Doupe, P K Kuhl
Aug 24, 2000·The Journal of the Acoustical Society of America·B RossC Pantev
Sep 9, 2000·Journal of Neurophysiology·A L GiraudA Kleinschmidt
Nov 8, 2001·Proceedings of the National Academy of Sciences of the United States of America·E AhissarM M Merzenich
Feb 19, 2002·Trends in Cognitive Sciences·Robert J. ZatorreVirginia B. Penhune
Mar 8, 2002·Nature·Zachary M SmithAndrew J Oxenham
Jun 7, 2003·International Journal of Audiology·Terence W PictonDavid Purcell
Feb 6, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mounya ElhilaliShihab A Shamma
Apr 1, 2004·Cerebral Cortex·Catherine Liégeois-ChauvelPatrick Chauvel
Jan 29, 2005·Proceedings of the National Academy of Sciences of the United States of America·Fan-Gang ZengKeli Cao
Feb 22, 2005·Nature Neuroscience·Anthony BoemioDavid Poeppel
Jul 20, 2005·Journal of Neuroscience Methods·Jonathan Z Simon, Yadong Wang

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Citations

Nov 16, 2012·Proceedings of the National Academy of Sciences of the United States of America·Molly J Henry, Jonas Obleser
Aug 21, 2009·Journal of Neurophysiology·Nai Ding, Jonathan Z Simon
Nov 26, 2008·Cognitive Processing·Maurizio De PittàEshel Ben-Jacob
Oct 1, 2014·Proceedings of the National Academy of Sciences of the United States of America·Molly J HenryJonas Obleser
Jan 9, 2007·Hearing Research·Huan LuoDavid Poeppel
Nov 3, 2010·The European Journal of Neuroscience·Garreth PrendergastGary G R Green
Feb 27, 2013·Dyslexia : the Journal of the British Dyslexia Association·Alida AndersonMin Wang
Aug 13, 2013·Hearing Research·Christian F Altmann, Bernhard H Gaese
Apr 1, 2014·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Kate L Christison-LagayYale E Cohen
Dec 14, 2017·Scientific Reports·Francisco Cervantes Constantino, Jonathan Z Simon
Nov 8, 2018·The European Journal of Neuroscience·Adam M GiffordYale E Cohen
Oct 28, 2008·Journal of Speech, Language, and Hearing Research : JSLHR·Josiane BertonciniChristian Lorenzi
Dec 5, 2016·The Journal of the Acoustical Society of America·Naveen K Nagaraj
Apr 12, 2011·Reviews in the Neurosciences·Kirill V Nourski, John F Brugge

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