Conditional Survival of Esophageal Cancer: An Analysis from the SEER Registry (1988-2011)

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer
Ellen KimCharles R Thomas

Abstract

Conditional survival can provide valuable predictive information for both patients and caregivers for patients surviving over time. The purpose of this study was to estimate conditional survival for esophageal cancer patients through analysis of a national population-based cancer registry. This retrospective cohort study analyzed 64,433 patients within the Surveillance, Epidemiology, and End Results (SEER) data set who were diagnosed with esophageal cancer from 1988 to 2011. Covariates included cancer characteristics and demographics. Overall survival (defined as time from diagnosis until death), cause-specific survival (defined as time from diagnosis until death from cancer), and 5-year conditional survivals (the probability of surviving an additional 5 years) were calculated. Significant prognostic variables of univariate and multivariable models of survival were identified. The multivariable models of overall and cause-specific survivals included gender, age group, race, relationship status, year of diagnosis, site, grade, histology, and stage group. Although all patients showed an improvement in conditional survival over time, more dramatic improvements were seen in more advanced stage groups. At the 5-year mark, conditiona...Continue Reading

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Citations

May 18, 2016·Scientific Reports·Marie-Pier TetreaultJonathan P Katz
Mar 16, 2018·Expert Review of Gastroenterology & Hepatology·Guoqing ZhangLongshuan Zhao
May 18, 2017·Gastroenterology Research and Practice·Xianlan ZhuLianzhen Yu
Jun 19, 2019·Journal of Orthopaedic Surgery and Research·Jin-Feng HuangAi-Min Wu
Feb 6, 2020·The British Journal of Surgery·E R C HagensS S Gisbertz
Sep 12, 2017·Expert Review of Anticancer Therapy·Omar Abdel-Rahman

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