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Conditional U1 Gene Silencing in Toxoplasma gondii

bioRxiv

Sep 1, 2014

Manuela S PieperhoffMarkus V Meissner

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Abstract

In absence of powerful siRNA approaches, the functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencin...read more

Mentioned in this Paper

Exons
Genes
Introns
Molecular Probe Techniques
MRNA Precursor
Parasites
Plasmodium falciparum
Protein C
Heterogeneous Nuclear RNA
RNA, Messenger
3
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  • Conditional U1 Gene Silencing in Toxoplasma gondii

    bioRxiv

    Sep 1, 2014

    Manuela S PieperhoffMarkus V Meissner

    PMID: 990008649

    DOI: 10.1101/008649

    Abstract

    In absence of powerful siRNA approaches, the functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencin...read more

    Mentioned in this Paper

    Exons
    Genes
    Introns
    Molecular Probe Techniques
    MRNA Precursor
    3

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