PMID: 9194053May 1, 1997Paper

Conditioned defensive reflex in the edible snail (molecular-genetic aspects)

Neuroscience and Behavioral Physiology
L N GrinkevichP D Lisachev

Abstract

The expression of the early genes c-fos and c-jun were studied by blot hybridization in the central nervous system of the edible snail at the consolidation stage of a conditioned defensive reflex, with the aim of investigating genomic activity in neurons during learning. The c-fos gene was shown to be present in the Helix central nervous system, and its expression was shown to increase significantly during learning. Superinduction of the c-fos gene was observed in the presence of cycloheximide, a protein synthesis inhibitor. Corasol also induced this gene. Thus, induction of the c-fos gene in Helix can be induced by agents which induce it in higher vertebrates. This suggests that expression of the c-fos gene in Helix and in higher vertebrates is regulated by closely related mechanisms. Expression of the c-jun gene was insignificant, and definitive conclusions with regard to the role of this gene in learning cannot be drawn.

References

Oct 1, 1992·Trends in Biochemical Sciences·M Karin, T Smeal
Sep 3, 1987·Nature·S M GreenbergJ H Schwartz
Oct 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·T J Nelson, D L Alkon
Sep 1, 1986·Neuroscience Research·E R KandelP Goelet
Jan 1, 1993·Annual Review of Neuroscience·R C Armstrong, M R Montminy
Jan 1, 1991·The European Journal of Neuroscience·Konstantin V. Anokhin, Steven P. R. Rose

❮ Previous
Next ❯

Citations

Oct 2, 2007·Neurobiology of Learning and Memory·Jelena Radulovic, Natalie C Tronson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved