PMID: 6990086Apr 1, 1980Paper

Conduction of excitation along the myocardium of the transplanted heart

Kardiologiia
E V Tiurina

Abstract

Changes in the sequence of the stimulation of the epicardial surface of a transplanted heart were studied on a heterotopic model in dogs in different periods after the operation. It was found that in the first hours the disturbances in stimulation are diffuse, but later they are of a more restricted character. These disturbances disappear completely by the 2nd day. On the 3rd-4th day the disorders of stimulation conduction reappear in limited areas, which corresponds with the developing focal morphological changes. The gradual increase in the area of disturbed stimulation conduction and in the intensity of the damage by the time of the rejection crisis were attended by a decrease of the P wave amplitude, deceleration of heart beats, development of atrioventricular block, the occurrence of heterotopic impulses, and disorganization of ventricular stimulation.

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.