PMID: 3653890Oct 1, 1987Paper

Confined chorionic mosaicism in prenatal diagnosis

Human Genetics
D K KalousekR D Wilson

Abstract

Confined chorionic mosaicism, detected commonly on chorionic villus sampling (CVS) and occasionally in cultured amniotic fluid cells, is described in five pregnancies that showed confined chorionic mosaicism for trisomies 12, 13, 14, 17 and a marker chromosome. Cytogenetic findings in these pregnancies support the conclusion that within chorion some chromosomal mosaicism are confined to the trophectoderm derivatives while others to the extra-embryonic mesoderm. The etiology of confined chorionic mosaicism is discussed in relation to a significant role of multiple cell lineages contributing to the early development of placenta. The need is indicated for the use of both direct and long-term cultures in CVS prenatal diagnosis, and for the confirmatory testing of fetal blood or amniotic fluid in cases where mosaicism is detected in chorionic villi.

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Citations

Aug 1, 1996·Prenatal Diagnosis·C GroliS Zaglio
Nov 14, 1997·Prenatal Diagnosis·C Van den BergF J Los
Jun 22, 2000·Prenatal Diagnosis·A H NassarD Martin
Jul 1, 1990·Prenatal Diagnosis·K S ReddyV Corson
Dec 1, 1990·Prenatal Diagnosis·R Petrella, K Hirschhorn
Jun 1, 1991·Prenatal Diagnosis·M DjalaliD Grab
Aug 1, 1991·Prenatal Diagnosis·I KennerknechtR Terinde
May 1, 1992·Prenatal Diagnosis·D H LedbetterK L Copeland
Jun 1, 1992·Prenatal Diagnosis·L J SciorraM S Dimaio
Jun 1, 1992·Prenatal Diagnosis·J Lähdetie, T Lakkala
Aug 1, 1992·Prenatal Diagnosis·M DjalaliR Terinde
Dec 1, 1992·Prenatal Diagnosis·J G Post, J G Nijhuis
Jan 1, 1993·Prenatal Diagnosis·J D LiouT L Yang-Feng
Apr 1, 1993·Prenatal Diagnosis·N Morichon-DelvallezM Vekemans
Mar 1, 1989·Somatic Cell and Molecular Genetics·T K MohandasL J Shapiro
Jan 14, 1993·The New England Journal of Medicine·M E D'Alton, A H DeCherney
Jan 1, 1993·Journal of Medical Genetics·J W DixonI E Teshima
Jul 1, 1996·Journal of Medical Genetics·D K Kalousek, M Vekemans
Nov 15, 2011·Gynécologie, obstétrique & fertilité·J CalooneR-C Rudigoz
Apr 20, 2010·Mutation Research·Robert P Erickson
Oct 14, 2004·American Journal of Medical Genetics. Part a·Paulien TerhalJacques Giltay
Oct 15, 2011·American Journal of Medical Genetics. Part a·Robert DaberNancy B Spinner
Mar 25, 2016·Studies in History and Philosophy of Biological and Biomedical Sciences·Andrew J Hogan
Nov 1, 1989·American Journal of Reproductive Immunology : AJRI·T Y Khong, K T Yee

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