PMID: 3653890Oct 1, 1987Paper

Confined chorionic mosaicism in prenatal diagnosis

Human Genetics
D K KalousekR D Wilson


Confined chorionic mosaicism, detected commonly on chorionic villus sampling (CVS) and occasionally in cultured amniotic fluid cells, is described in five pregnancies that showed confined chorionic mosaicism for trisomies 12, 13, 14, 17 and a marker chromosome. Cytogenetic findings in these pregnancies support the conclusion that within chorion some chromosomal mosaicism are confined to the trophectoderm derivatives while others to the extra-embryonic mesoderm. The etiology of confined chorionic mosaicism is discussed in relation to a significant role of multiple cell lineages contributing to the early development of placenta. The need is indicated for the use of both direct and long-term cultures in CVS prenatal diagnosis, and for the confirmatory testing of fetal blood or amniotic fluid in cases where mosaicism is detected in chorionic villi.


Jan 1, 1978·American Journal of Medical Genetics·H HoehnC L Maxwell
Jun 1, 1986·American Journal of Obstetrics and Gynecology·A O MartinS Elias
Apr 1, 1986·Human Genetics·M J Vekemans, T B Perry
Mar 1, 1986·Human Genetics·G SimoniS Porta
Apr 1, 1985·Journal of Medical Genetics·B BrambatiM Fraccaro
Jun 1, 1974·Pediatric Research·D M CoxJ L Hamerton
Jan 1, 1969·British Medical Bulletin·C E Ford
Jul 1, 1984·Prenatal Diagnosis·P K JensenU Friedrich
Sep 1, 1984·Prenatal Diagnosis·R A PfeifferE Wagner-Thiessen
Aug 12, 1983·Science·D K Kalousek, F J Dill
Jan 1, 1982·American Journal of Medical Genetics·F GreenbergL B Stone
Jul 15, 1981·American Journal of Obstetrics and Gynecology·G Stetten, H I Meissner

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