Confinement and partitioning of a single polymer chain in a dense array of nanoposts

Soft Matter
Heesun Joo, Jun Soo Kim

Abstract

We present a Brownian dynamics simulation study on the confinement and partitioning of a single, flexible polymer chain in a dense array of nanoposts with different sizes and separations, especially, when the volume of an interstitial space formed among four nanoposts is less than the volume of the polymer chain. As the interstitial volume decreases by either increasing the nanopost diameter or decreasing the separation between nanoposts, the chain conformation becomes elongated in the direction parallel to the nanoposts. Interestingly, however, the degree of chain elongation varies in a non-monotonic fashion as the interstitial volume decreases while keeping the passage width between two nanoposts constant at a small value. We calculate the free energy of chain partitioning over several interstitial spaces from the partitioning probability, and find that the non-monotonic dependence of the chain elongation results from an interplay between the confinement-driven chain elongation along the direction parallel to the nanoposts and the chain spreading perpendicular to the nanoposts by partitioning chain segments over several interstitial spaces. These results present the possibility of utilizing a dense array of nanoposts as a tem...Continue Reading

References

Aug 13, 1992·Nature·W D Volkmuth, R H Austin
Feb 1, 1996·Journal of Molecular Graphics·W HumphreyK Schulten
May 1, 1986·Physical Review. B, Condensed Matter·Y Chen, M Muthukumar
Jan 17, 2002·Analytical Chemistry·O BakajinE C Cox
Mar 23, 2002·Science·Patrick S DoyleJean-Louis Viovy
Aug 10, 2002·Science·Dmytro NykypanchukDavid A Hoagland
Oct 19, 2005·The Journal of Chemical Physics·Bong June Sung, Arun Yethiraj
May 11, 2006·Nano Letters·Angelo Cacciuto, Erik Luijten
Jan 6, 2009·Proceedings of the National Academy of Sciences of the United States of America·Walter ReisnerAnders Kristensen
Mar 5, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Greg Morrison, D Thirumalai
Apr 2, 2009·The Journal of Chemical Physics·Bong June SungArun Yethiraj
Aug 8, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Youngkyun JungBae-Yeun Ha
Dec 9, 2009·The Journal of Chemical Physics·Erica J Saltzman, Murugappan Muthukumar
Mar 9, 2010·Nature Nanotechnology·Sheng ShenGang Chen
Jun 4, 2010·Journal of Cell Science·Natalia Naumova, Job Dekker
Aug 24, 2011·Macromolecules·Yanwei WangKevin D Dorfman
Dec 17, 2011·Advanced Materials·Suhao WangKlaus Müllen
Mar 1, 2012·The Journal of Chemical Physics·Zhixiang ZouLong Wang
Aug 22, 2012·The Journal of Physical Chemistry. B·Mark R Smyda, Stephen C Harvey
Sep 15, 2012·Reports on Progress in Physics·Walter ReisnerRobert H Austin
Dec 7, 2013·Electrophoresis·Yannick VieroAurélien Bancaud
May 17, 2013·Physical Review Letters·Douglas R TreeKevin D Dorfman

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Citations

Oct 11, 2017·The Journal of Chemical Physics·Zuzana BenkováPeter Cifra
Oct 5, 2017·Electrophoresis·Matthew C VandeSandeHendrick W de Haan
Apr 10, 2019·Polymers·Lucia RišpanováPeter Cifra
Apr 16, 2020·Physical Review. E·Kye Hyoung KilJun Soo Kim

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