PMID: 11909505Mar 23, 2002Paper

Confinement-induced entropic recoil of single DNA molecules in a nanofluidic structure

Physical Review Letters
S W P TurnerH G Craighead

Abstract

The behavior of DNA molecules is observed in a nanofluidic device near the interface of two regions that produce different configuration entropies. An electric field is applied to drive the molecules partway across the interface. Upon removal of the field, the molecules recoil to the higher-entropy region with a profile characteristic of a force localized to the interface and independent of length. This is consistent with a confinement-mediated entropic force, distinct from the well-known entropic elasticity common to all polymers. An estimate of the hydrodynamic drag is used to produce a lower bound for the force. The phenomenon can be exploited to separate long-strand polyelectrolytes according to length.

References

Jan 1, 1991·Annual Review of Biophysics and Biophysical Chemistry·C Bustamante
Sep 9, 1994·Science·C BustamanteS Smith
Sep 9, 1991·Physical Review Letters·E Arvanitidou, D Hoagland

❮ Previous
Next ❯

Citations

Mar 15, 2008·Analytical and Bioanalytical Chemistry·Nicholas DouvilleShuichi Takayama
Feb 24, 2009·Analytical and Bioanalytical Chemistry·Han J G E Gardeniers
Oct 29, 2003·Current Opinion in Biotechnology·Randolph AshtonRavi S Kane
Apr 29, 2006·Analytical Chemistry·Kyung Eun Sung, Mark A Burns
Dec 14, 2012·Analytical Chemistry·Laurent D Menard, J Michael Ramsey
May 9, 2013·Nature Communications·Oliver OttoKlaus Kroy
Jan 16, 2013·Proceedings of the National Academy of Sciences of the United States of America·Sun-Hae HongHarley H McAdams
Oct 13, 2006·Journal of Aerosol Medicine : the Official Journal of the International Society for Aerosols in Medicine·Yvonne K LentzCorinne S Lengsfeld
Jun 1, 2010·Nucleic Acids Research·Katrin GüntherRalf Seidel
Nov 23, 2006·Journal of Nanobiotechnology·Fabio Baldessari, Juan G Santiago
Jul 26, 2006·The Journal of Chemical Physics·Tingting SunJiaye Su
Apr 21, 2007·The Journal of Chemical Physics·Kaifu LuoAniket Bhattacharya
Mar 25, 2006·The Journal of Chemical Physics·Kaifu LuoSee-Chen Ying
Jan 3, 2013·The Journal of Chemical Physics·Wancheng YuKaifu Luo
Oct 4, 2006·The Journal of Chemical Physics·Ilkka HuopaniemiSee-Chen Ying
Jan 26, 2010·The Journal of Chemical Physics·Amir Houshang Bahrami, Mir Abbas Jalali
Jan 28, 2006·The Journal of Chemical Physics·Kaifu LuoSee-Chen Ying
May 13, 2006·The Journal of Chemical Physics·Yongjun XieJie Chen
Jan 21, 2014·The Journal of Chemical Physics·Pei-Ren JengY C Chou
Jun 18, 2005·Proceedings of the National Academy of Sciences of the United States of America·Michal TokarzOwe Orwar
Oct 18, 2003·Proceedings of the National Academy of Sciences of the United States of America·Christiane A OpitzWolfgang A Linke
Aug 3, 2014·The Journal of Chemical Physics·Huaping LiHaojun Liang
Mar 15, 2008·Biophysical Journal·Christian H RecciusH G Craighead
Mar 11, 2016·Analytical Chemistry·Kumuditha Madushanka Weerakoon RatnayakeSteven Allan Soper
Jul 9, 2004·Biophysical Journal·Jonathan NakaneAndre Marziali
Nov 9, 2016·The Journal of Chemical Physics·Mingfeng PuZhonghuai Hou
Sep 16, 2004·The Journal of Chemical Physics·Andrey MilchevAniket Bhattacharya
Dec 21, 2007·Lab on a Chip·Jongyoon HanReto B Schoch
Dec 24, 2016·Lab on a Chip·Kumuditha M Weerakoon-RatnayakeSteven A Soper
Jan 20, 2018·Physical Review. E·Francesca Ruggeri, Madhavi Krishnan
Jul 13, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·M N Popescu, S Dietrich
May 26, 2006·Analytical and Bioanalytical Chemistry·Noritada KajiYoshinobu Baba
May 25, 2007·Journal of Physics A: Mathematical and General·Maria R D'OrsognaTibor Antal
Apr 28, 2005·Lab on a Chip·D MijatovicA van den Berg
May 9, 2008·Analytical and Bioanalytical Chemistry·Hideki NabikaKei Murakoshi
Aug 15, 2009·Lab on a Chip·G B Salieb-BeugelaarJ C T Eijkel
Nov 10, 2009·Nature Nanotechnology·W SparreboomJ C T Eijkel
Feb 25, 2010·Chemical Society Reviews·Stephen L Levy, Harold G Craighead
Apr 2, 2010·Lab on a Chip·M NapoliS Pennathur
Sep 15, 2010·Physical Chemistry Chemical Physics : PCCP·Li-Zhen SunMeng-Bo Luo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved