Confirmation of association of protein I serotype of Neisseria gonorrhoeae with ability to cause disseminated infection.

Infection and Immunity
J G CannonP F Sparling

Abstract

Previous work indicates that strains of Neisseria gonorrhoeae isolated in Seattle, Wash., and Atlanta, Ga., show an association between serotypes 1 and 2 of protein I of the outer membrane and the ability to cause disseminated infection (T.M. Buchanan and J.F. Hildebrandt, Infect. Immun. 32:985-994, 1981). By using the same serotyping system, we confirmed the association between those serotypes and both disseminated infection and serum resistance in strains from North Carolina. Some strains of the same serotype had protein I species with different apparent molecular weights.

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Citations

Sep 9, 1998·The Journal of Experimental Medicine·J P van PuttenJ Carlson
Nov 9, 2005·Proceedings of the National Academy of Sciences of the United States of America·Jutamas NgampasutadolPeter A Rice
Sep 10, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sarika AgarwalPeter A Rice
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