PMID: 2096162Nov 1, 1990Paper

Confirmation of high blood flow rates through 150 mu filter/high-flow tubing

The Journal of Emergency Medicine
K V Iserson, M A Knauf

Abstract

Many new products designed to assist in rapid blood infusion are appearing. Some highly touted and routinely used devices for intravenous (IV) infusion have recently been shown to be, at least in part, defective. A tubing with an in-line 150 mu filter (150 mu High-Flow Blood Filter; Saftifilter Blood Administration Sets; Cutter Biological, Berkeley, CA 94710) has recently been introduced to facilitate rapid blood transfusion. It is claimed that at least 8.5 units of blood can be rapidly run through each set before replacement is necessary. To test this under simulated clinical conditions, four sets of ten random units of outdated erythrocytes at 4 to 9 degrees C were each admixed with 250 mL 70 degrees C 0.9 NaCl and infused through the system under a constant 300 mmHg pressure. Two sets infused through unmodified tubing flowed at an average of 25 mL/sec (1500 mL/min) before there was an appreciable slowing of the flow rate. Two sets with 8 Fr catheters attached infused at an average of 22 mL/sec (1320 mL/min) before there was an appreciable slowing of the flow rate. Even after the flow slowed, the 9th and 10th units infused at an average greater than 10 mL/sec (600 mL/min). The tubing/filter exceeded the manufacturer's publish...Continue Reading

References

Mar 1, 1988·Transfusion·E B WilsonK V Iserson
Sep 1, 1987·Archives of Emergency Medicine·G D Cross
Apr 1, 1987·Annals of Emergency Medicine·E B Wilson, K V Iserson
Jan 1, 1985·The Journal of Emergency Medicine·K V IsersonE Criss

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