Confocal laser endomicroscopy: potential in the management of Barrett's esophagus

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
V J A KondaI Waxman

Abstract

Confocal laser endomicroscopy (CLE) can serve as a useful adjunct imaging modality for targeted endoscopic biopsies during surveillance of Barrett's esophagus (BE). In addition, CLE may also have potential roles during therapeutic procedures that include localization of pathology, targeting of resections, guiding which therapy to use, and determining adequacy of treatment. This case series illustrates a range of cases in which endomicroscopy was performed during the procedure and offers possibilities of real-time decision-making to select specific therapies in patients with known high-grade dysplasia (HGD) and intramucosal carcinoma in the setting of BE presented for endoscopic treatment or follow-up. Patients with BE with HGD and intramucosal carcinoma presented for management for initial treatment or follow-up. Examinations were performed sequentially with detailed white light endoscopy, narrow band imaging (NBI), acetic acid, and CLE. This is a retrospective case series describing the characteristics of the exam findings and illustrating the role of endomicroscopy on real-time case management. Seven patients with Barrett-associated neoplasia underwent endomicroscopy as part of their endoscopic examination. CLE confirmed find...Continue Reading

References

Jun 4, 2005·Endoscopy·UNKNOWN Endoscopic Classification Review Group
Sep 28, 2005·Gastrointestinal Endoscopy·Bergein F OverholtUNKNOWN International Photodynamic Group for High-Grade Dysplasia in Barrett's Esophagus
Jul 18, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ralf KiesslichMarkus F Neurath
Jul 25, 2006·Gastrointestinal Endoscopy·Prateek SharmaAllan Weston
Aug 11, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Alexander MeiningChristian Prinz
Jun 28, 2008·Gastrointestinal Endoscopy·Kevin K LeungSharmila Anandasabapathy
May 29, 2009·The New England Journal of Medicine·Nicholas J ShaheenCharles J Lightdale

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Citations

Nov 28, 2012·World Journal of Gastroenterology : WJG·Giovanni D De Palma
Apr 5, 2012·Gastroenterology Research and Practice·Helga BertaniRita Conigliaro

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