PMID: 9436159Jan 22, 1998Paper

Confocal microscopy as a tool for the investigation of the anterior part of the eye

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
P FurrerR Gurny

Abstract

In recent years, confocal microscopy has become a powerful tool for examining microscopic structures in the living eye. The decisive advantage of this technique is that it permits the investigation of optical sections of relatively thick (> 10 microns) specimens. Because confocal microscopy suppresses the out-of-focus blur, sharp three-dimensional images with excellent resolution can be obtained. Confocal microscopy is therefore able to provide more information than the classic methods--i.e., specular microscopy and slit-lamp biomicroscopy. This paper reviews recent applications of confocal microscopy in three fields of ophthalmology: the observation of the anatomy of the anterior parts of the eye, the investigation of these structures after local administration of drugs and, finally, the use of this technique for the diagnosis of infectious ocular diseases.

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Citations

Apr 27, 2002·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Pascal FurrerRobert Gurny
Feb 3, 2005·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·S S SamudreJ D Sheppard
Jan 25, 2003·The British Journal of Ophthalmology·I JalbertM Coroneo
Apr 26, 2005·International Journal of Pharmaceutics·F LallemandR Gurny
Jun 7, 2002·AAPS PharmSci·Pascal FurrerRobert Gurny

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