Confocal Microscopy in Skin Cancer

Current Dermatology Reports
Verena Ahlgrimm-SiessAlon Scope

Abstract

Reflectance confocal microscopy (RCM) enables imaging of skin lesions at cellular level resolution at the bedside (in vivo) or in freshly excised tissue (ex vivo). This article provides an overview of strengths and limitations of non-invasive RCM in skin cancer diagnosis. RCM features of common melanocytic and non-melanocytic skin neoplasms such as melanoma, actinic keratosis/squamous cell carcinoma, basal cell carcinoma, and nevi have been well defined and show good correlation with dermoscopic and histopathologic findings. Due to its technical properties, RCM is especially suitable for the examination of flat skin lesions. In vivo RCM has been shown to increase the accuracy of non-invasive diagnosis of common skin neoplasms and is a valuable adjunct to dermoscopy, particularly in cosmetically and functionally sensitive areas such as the face or the genital area.

References

Jun 23, 2000·Journal of the American Academy of Dermatology·D AghassiS González
Jun 16, 2001·The Journal of Investigative Dermatology·M HuzairaS González
Aug 21, 2001·Journal of the American Academy of Dermatology·R G LangleyR R Anderson
Nov 27, 2002·Journal of the American Academy of Dermatology·Salvador González, Zeina Tannous
Aug 25, 2005·The Journal of Investigative Dermatology·Giovanni PellacaniStefania Seidenari
Jul 17, 2007·Journal of the American Academy of Dermatology·Alon ScopeSalvador Gonzalez
Jul 28, 2007·The Journal of Investigative Dermatology·Giovanni PellacaniScott Menzies
Dec 17, 2008·Archives of Dermatology·Giovanni PellacaniStefania Seidenari
Apr 29, 2009·Journal of the American Academy of Dermatology·Juliana Casagrande Tavoloni BragaAshfaq A Marghoob
May 2, 2009·Journal of the American Academy of Dermatology·Sonia SeguraJosep Malvehy
Jul 2, 2009·The British Journal of Dermatology·V Ahlgrimm-SiessR Hofmann-Wellenhof
Jul 22, 2009·Archives of Dermatology·Ayelet RishponHarold S Rabinovitz
Jan 18, 2013·JAMA Dermatology·Edith ArzbergerRainer Hofmann-Wellenhof
May 11, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·G PellacaniC Longo
Apr 15, 2014·Journal of the American Academy of Dermatology·Ivette AlarconSusana Puig
Apr 23, 2014·Experimental Dermatology·Giovanni PellacaniCaterina Longo
Apr 24, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·E MoscarellaC Longo
Oct 11, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·B FerrariG Pellacani
Aug 21, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·D J KadouchM A de Rie
Oct 4, 2016·Dermatologic Clinics·Melissa Gill, Salvador González
Apr 22, 2017·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Martin LaimerVerena Ahlgrimm-Siess
Aug 18, 2017·The American Journal of Dermatopathology·Neda ShahriariAlon Scope

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Citations

Feb 19, 2019·International Journal of Dermatology·Maria ContaldoAlberta Lucchese
Oct 31, 2018·Archives of Pathology & Laboratory Medicine·Savitri KrishnamurthySharjeel Sabir
Oct 26, 2018·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Francesco LacarrubbaGiuseppe Micali
Mar 15, 2019·Expert Review of Anticancer Therapy·Marina AgozzinoGiuseppe Argenziano
Jul 10, 2019·International Journal of Dermatology·Maria ContaldoAlberta Lucchese
Dec 19, 2019·Current Opinion in Oncology·Roberta GiuffridaIris Zalaudek
Mar 20, 2020·The Journal of Dermatological Treatment·Jade G M LoggerRieke J B Driessen
Sep 18, 2018·Expert Opinion on Pharmacotherapy·Elena CampioneLuca Bianchi
Jan 11, 2020·Frontiers in Oncology·Angela Filoni, Mauro Alaibac
Jan 15, 2021·Cell Biochemistry and Biophysics·Sharareh TavaddodHossein Naderi-Manesh
Jan 6, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·M SuppaV Del Marmol
Jan 7, 2021·Sensors·Laura Rey-BarrosoSantiago Royo
Jun 22, 2021·Archives of Dermatological Research·Fernanda Berti Rocha MendesGisele Gargantini Rezze
Nov 8, 2018·Dermatology : International Journal for Clinical and Investigative Dermatology·Francesca PeccerilloFrancesca Farnetani
Nov 19, 2021·Archives of Dermatological Research·Antonella TammaroGiovanni Pellacani

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Methods Mentioned

BETA
biopsies
imaging techniques
biopsy.
Confocal
biopsy

Software Mentioned

Vivastack
Vivablock

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