Confocal Raman microscopy of optical-trapped particles in liquids

Annual Review of Analytical Chemistry
Daniel P Cherney, Joel M Harris

Abstract

The in situ analysis of small, dispersed particles in liquids is a challenging problem, the successful solution to which influences diverse applications of colloidal particles in materials science, synthetic chemistry, and molecular biology. Optical trapping of small particles with a tightly focused laser beam can be combined with confocal Raman microscopy to provide molecular structure information about individual, femtogram-sized particles in liquid samples. In this review, we consider the basic principles of combining optical trapping and confocal Raman spectroscopy, then survey the applications that have been developed through the combination of these techniques and their use in the analysis of particles dispersed in liquids.

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Citations

Dec 12, 2012·Analytical Chemistry·Shailabh KumarSang-Hyun Oh
Mar 6, 2015·Applied Spectroscopy·Jay P KittJoel M Harris
Jan 9, 2019·Nanoscale·Sergei G KruglikJuan M Falcón-Pérez
Oct 17, 2018·Nature Communications·Jelle PendersMolly M Stevens
Sep 20, 2017·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Erhan Süleymanoğlu
Jan 23, 2021·Applied Microbiology and Biotechnology·Shuaishuai YanQing Liu
Jul 19, 2012·Analytical Chemistry·Yuewu XiaoMarta Portoles
Jan 27, 2012·Chemical Reviews·Francisco Zaera

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Methods Mentioned

BETA
rheology
light scattering
electron microscopy
Raman
confocal microscopy
Raman microscopy
X-ray
environmental stresses

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