Conformational control of Pd2L4 assemblies with unsymmetrical ligands.

Chemical Science
James E M LewisKim E Jelfs

Abstract

With increasing interest in the potential utility of metallo-supramolecular architectures for applications as diverse as catalysis and drug delivery, the ability to develop more complex assemblies is keenly sought after. Despite this, symmetrical ligands have been utilised almost exclusively to simplify the self-assembly process as without a significant driving foa mixture of isomeric products will be obtained. Although a small number of unsymmetrical ligands have been shown to serendipitously form well-defined metallo-supramolecular assemblies, a more systematic study could provide generally applicable information to assist in the design of lower symmetry architectures. Pd2L4 cages are a popular class of metallo-supramolecular assembly; research seeking to introduce added complexity into their structure to further their functionality has resulted in a handful of examples of heteroleptic structures, whilst the use of unsymmetrical ligands remains underexplored. Herein we show that it is possible to design unsymmetrical ligands in which either steric or geometric constraints, or both, can be incorporated into ligand frameworks to ensure exclusive formation of single isomers of three-dimensional Pd2L4 metallo-supramolecular assem...Continue Reading

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Citations

Dec 21, 2019·Chemical Communications : Chem Comm·Song-Bo LuWei Jiang
May 5, 2020·ChemPlusChem·James E M Lewis, James D Crowley
Aug 5, 2020·Chemical Communications : Chem Comm·Kevin Kei Gwan WongJames E M Lewis
May 18, 2021·Chemistry : a European Journal·Ru-Jin LiKay Severin
Nov 27, 2020·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Shuichi HiraokaHirofumi Sato
Nov 28, 2020·Angewandte Chemie·Irene RegeniGuido H Clever
Dec 23, 2020·Chemistry : a European Journal·Francesca GuagniniChiara Massera
Jan 7, 2021·Chemistry : a European Journal·James E M Lewis
Feb 23, 2021·Chemical Communications : Chem Comm·Adrian W Markwell-HeysWitold M Bloch
Jun 25, 2021·Chemical Science·Sonja PullenGuido H Clever
Apr 27, 2021·Journal of the American Chemical Society·Jacopo TessaroloGuido H Clever
Sep 16, 2020·Journal of the American Chemical Society·Jianzhu WangPaul J Lusby
Sep 23, 2021·Inorganic Chemistry·Balamurugan KandasamyLeroy Cronin

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Methods Mentioned

BETA
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