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Conformational fingerprinting of the angiotensin I-converting enzyme (ACE). 1. Application in sarcoidosis

Journal of Proteome Research

Sep 30, 2010

Sergei M DanilovJoe G N Garcia

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Abstract

Fine epitope mapping of monoclonal antibodies (mAbs) to 16 epitopes on human angiotensin I-converting enzyme (ACE) revealed that the epitopes of all mAbs contained putative glycosylation sites. ACE glycosylation is both cell- and tissue-specific and, therefore, the local conformation of...read more

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Conformational fingerprinting of the angiotensin I-converting enzyme (ACE). 1. Application in sarcoidosis

Journal of Proteome Research

Sep 30, 2010

Sergei M DanilovJoe G N Garcia

PMID: 20873814

DOI: 10.1021/pr100564r

Abstract

Fine epitope mapping of monoclonal antibodies (mAbs) to 16 epitopes on human angiotensin I-converting enzyme (ACE) revealed that the epitopes of all mAbs contained putative glycosylation sites. ACE glycosylation is both cell- and tissue-specific and, therefore, the local conformation of...read more

Mentioned in this Paper

Ovarian Diseases
Monoclonal Antibodies
Monoclonal antibodies, antineoplastic
Chinese Hamster
N-(2-acetamido)-2-aminoethanesulfonic acid
Lung
Spleen
Both Ovaries
Bone Marrow
Antigenic Specificity

Feeds With Similar Papers

Immune Therapies In Cancer

Immunotherapy in cancer is used to help the immune system fight against invading cancer cells. It is used to slow the progression of the disease and prevent metastasis while enhancing the immune response. There are different types, including monoclonal antibodies and checkpoint inhibitors. Here is the latest research on immune therapies in cancer.

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References
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  • Citations12
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    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations12
12

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