PMID: 2107612Jan 1, 1990Paper

Conformational stability of globular proteins

Trends in Biochemical Sciences
C N Pace

Abstract

The conformational stability of ribonuclease T1 has been measured as a function of the variables of most interest to biochemists: temperature, pH, salt concentration, disulfide-bond content and amino acid sequence. The results provide insight into the forces that stabilize globular proteins.

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