Conformations and orientational ordering of semiflexible polymers in spherical confinement

The Journal of Chemical Physics
Andrey MilchevKurt Binder

Abstract

Semiflexible polymers in lyotropic solution confined inside spherical nanoscopic "containers" with repulsive walls are studied by molecular dynamics simulations and density functional theory, as a first step to model confinement effects on stiff polymers inside of miniemulsions, vesicles, and cells. It is shown that the depletion effects caused by the monomer-wall repulsion depend distinctly on the radius R of the sphere. Further, nontrivial orientational effects occur when R, the persistence length ℓp, and the contour length L of the polymers are of similar magnitude. At intermediate densities, a "shell" of wall-attached chains is forming, such that the monomers belonging to those chains are in a layer at about the distance of one monomer from the container wall. At the same time, the density of the centers of mass of these chains is peaked somewhat further inside, but still near the wall. However, the arrangement of chains is such that the total monomer density is almost uniform in the sphere, apart from a small layering peak at the wall. It is shown that excluded volume effects among the monomers are crucial to account for this behavior, although they are negligible for comparable isolated single semiflexible chains of the s...Continue Reading

References

Dec 1, 1989·Journal of Computer-aided Molecular Design·M P Allen, M R Wilson
Nov 1, 1973·Zeitschrift Für Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie·W Helfrich
May 1, 1986·Physical Review A: General Physics·G S Grest, K Kremer
Jun 1, 1995·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·M Dijkstra, D Frenkel
Mar 18, 2006·The Journal of Chemical Physics·M Hase, K Yoshikawa
Mar 21, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Yu Trukhina, T Schilling
Mar 5, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Greg Morrison, D Thirumalai
Sep 28, 2010·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Makiko NegishiKenichi Yoshikawa
Sep 28, 2010·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Katja OstermeirErwin Frey
Mar 15, 2011·Journal of Physics. Condensed Matter : an Institute of Physics Journal·D MarenduzzoE Orlandini
Sep 21, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Yuji HiguchiTakafumi Iwaki
Nov 15, 2011·Current Opinion in Solid State & Materials Science·Qi Wen, Paul A Janmey
Nov 22, 2011·Biophysical Journal·Dong MengJianzhong Wu
Aug 3, 2012·The Journal of Chemical Physics·Zhehui Jin, Jianzhong Wu
Sep 15, 2012·Reports on Progress in Physics·Walter ReisnerRobert H Austin
Jul 26, 2013·The Journal of Chemical Physics·Thijs van WestenJoachim Gross
Nov 26, 2013·Proceedings of the National Academy of Sciences of the United States of America·Davide MarenduzzoDe Witt Sumners
Oct 16, 2015·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Debabrata PanjaJ M J van Leeuwen
May 10, 2016·The Journal of Chemical Physics·Sergei A EgorovKurt Binder
May 21, 2016·Physical Review Letters·Sergei A EgorovKurt Binder
Aug 10, 2016·Polymers·Sergei A EgorovKurt Binder

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Citations

Jun 10, 2017·Physical Review Letters·Arash NikoubashmanAndrey Milchev
Sep 17, 2019·Cytoskeleton·Maral Adeli KoudehiDimitrios Vavylonis
May 3, 2019·The Journal of Chemical Physics·Nam-Kyung Lee, Albert Johner
Jul 28, 2020·The Journal of Chemical Physics·Jian Jiang
Mar 10, 2021·The Journal of Chemical Physics·Arash Nikoubashman

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