Congenital aortic valve disease. Improved survival and quality of life

Annals of Surgery
R C ElkinsM M Lane

Abstract

The purpose of the study was to assess the effect of recent trends in surgical management, including use of the Ross Operation, on improved survival and quality of life in patients treated surgically for aortic valve (AV) disease at Oklahoma Children's Hospital. Surgical treatment of congenital AV disease has proved to be palliative, but newer procedures may be improving outcomes. A retrospective review of 301 patients, age 1 day to 26 years (median, 5 years), having a surgical AV procedure or aortic balloon valvuloplasty at Children's Hospital of Oklahoma between 1960 and February 1996, was conducted. Information was collected on all prior and subsequent operations, and follow-up within 1 year was 96% complete. Survival for all patients was 90% +/- 2% at age 10 years and 73% +/- 8% at age 25. By age 5, 52% +/- 4% had required an AV procedure, 89% +/- 3% by age 15. Patient survival was affected adversely by the diagnosis of valvar aortic stenosis, 79% +/- 6% at age 25 compared to 95% +/- 4% for subvalvar aortic stenosis or aortic insufficiency (p = 0.01). The AV morphology did not affect survival, but patients with a bicuspid or unicuspid valve required operative intervention at an earlier age. Survival after autograft replacem...Continue Reading

References

Sep 1, 1992·The Annals of Thoracic Surgery·F M LupinettiE L Bove
Aug 1, 1990·The Annals of Thoracic Surgery·J R StewartH W Bender
Sep 1, 1988·Journal of Cardiac Surgery·D Ross
Sep 1, 1982·The American Journal of Cardiology·M JonesA G Morrow
Aug 1, 1995·The Annals of Thoracic Surgery·M F O'BrienS E Smith
May 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·E M BaudetN Laborde
Jun 1, 1994·The Annals of Thoracic Surgery·R C ElkinsM M Lane

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Citations

Mar 24, 2006·Cardiology in the Young·Kathleen A Mussatto, Kathleen A Mussato
Mar 21, 2002·Artificial Organs·F D da CostaE Matte
Dec 16, 2000·Cardiology in the Young·V LambertC Planche
Feb 16, 2021·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Manan Desai

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