Congenital corneal anesthesia in children with the VACTERL association

American Journal of Ophthalmology
J R CruysbergH G Brunner

Abstract

To describe ocular manifestations in patients with the VACTERL (vertebral, anal, cardiovascular, tracheoesophageal, renal, and limb defects) association. We reviewed the medical records of patients with the VACTERL association who had undergone treatment for amblyopia at the orthoptic department. A striking similarity was found in three unrelated children, who, in addition to clinical manifestations of VACTERL association, showed total corneal anesthesia of one or both eyes that had resulted in recurrent corneal erosions, keratitis, and permanent corneal opacities. Other ocular manifestations included nonparalytic strabismus, anisometropia, and amblyopia. Congenital corneal anesthesia may be part of the VACTERL association.

References

Jan 1, 1978·American Journal of Ophthalmology·M M Mohandessan, P E Romano
Jan 1, 1991·American Journal of Medical Genetics·A K IafollaY T Chen
Mar 1, 1988·The British Journal of Ophthalmology·L Esakowitz, J R Yates
Apr 1, 1988·Archives of Dermatology·N IshiiH Nakajima
Mar 1, 1986·American Journal of Diseases of Children·D D WeaverP L Yu

❮ Previous
Next ❯

Citations

Nov 11, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C SchüllerC H Meyer
Jan 11, 2007·Survey of Ophthalmology·K RamaeshB Dhillon
Sep 18, 2014·The British Journal of Ophthalmology·Rosemary G LambleyAsim Ali
Jun 9, 2004·Eye·A M MansourH I Salti
Mar 15, 2001·Cornea·M M MathenM Srinivasan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ophthalmic Paediatrics and Genetics
A TabuchiM Hirokawa
Ophthalmic Plastic and Reconstructive Surgery
A M Mansour, H K Li
© 2021 Meta ULC. All rights reserved