PMID: 15256994Jul 17, 2004Paper

Congenital corneal opacities in a cornea referral practice

Cornea
Renata A RezendeElisabeth J Cohen

Abstract

To address the primary causes of the congenital corneal opacities seen on the Cornea Service at Wills Eye Hospital (Philadelphia, PA), the associated systemic anomalies and their management. Retrospective review of the medical records of all patients with the diagnosis of congenital corneal opacities seen at the Cornea Service from January 1, 1992 to June 30, 2003. Children 12 years old or younger at the first visit to our department were included in the study. We classified the location and extent of corneal pathology. We divided the management into medical and surgical. Seventy-two eyes of 47 patients were included in the study. The mean follow-up time from the first to the last visit was 33.1 months. The most common primary cause of congenital corneal abnormalities was Peters anomaly (40.3%), followed by sclerocornea (18.1%), dermoid (15.3%), congenital glaucoma (6.9%), microphthalmia (4.2%), birth trauma, and metabolic disease (2.8%). Seven eyes (9.7%) were classified as idiopathic. Ten patients had systemic abnormalities associated with their ocular condition. The management was medical in 38 eyes (52.7%). Twenty-four eyes (32.4%) underwent only 1 penetrating keratoplasty (PK). Only 1 eye received a regraft during the foll...Continue Reading

References

Jul 1, 1975·Survey of Ophthalmology·G O WaringPeter R Laibson
Jan 1, 1992·International Ophthalmology Clinics·P R Cotran, A M Bajart
Mar 1, 1990·Ophthalmology·J W Cowden
Jul 1, 1989·Ophthalmology·C F LeeJ Sugar
Apr 15, 1987·American Journal of Ophthalmology·R M SteinR D Reinecke
Nov 15, 1987·American Journal of Ophthalmology·P A DeRespinis, R S Wagner
May 1, 1985·Archives of Ophthalmology·J H ElliottM Garber
Oct 1, 1984·Ophthalmology·R D StultingJ A Gammon
Dec 1, 1984·Ophthalmic Paediatrics and Genetics·M J van SchooneveldE M Bleeker-Wagemakers
Dec 1, 1980·Ophthalmology·D J SchanzlinS I Brown
Mar 1, 1994·Ophthalmic Genetics·S R GollamudiI H Maumenee
Mar 1, 1997·Archives of Ophthalmology·D VarssanoR C Eagle
Jan 22, 2002·The British Journal of Ophthalmology·K K NischalD S Rootman
Apr 16, 2003·Eye & Contact Lens·C Banu CosarChristopher J Rapuano

Citations

Jul 25, 2008·Cornea·Kavita V RaoVirender S Sangwan
Sep 18, 2010·Cornea·Mirjana Bjeloš RončevićLjubica Dorn Md
Jul 14, 2012·Cornea·Hassan HashemiMasomeh Mohebi
Apr 23, 2008·International Ophthalmology Clinics·Mona Harissi-Dagher, Kathryn Colby
Feb 21, 2006·The British Journal of Ophthalmology·R D YoungS Kinoshita
Oct 17, 2008·Orphanet Journal of Rare Diseases·Julie Desir, Marc Abramowicz
Jan 1, 2011·Digital Journal of Ophthalmology : DJO·Mona Harissi-Dagher
Oct 8, 2014·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Martina C HerwigAnnette M Müller
Dec 22, 2007·Seminars in Ophthalmology·Jessica Ciralsky, Kathryn Colby
Mar 3, 2015·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Anagha Medsinge, K K Nischal
Mar 21, 2009·Survey of Ophthalmology·M VanathiTanuj Dada
Jul 3, 2007·American Journal of Ophthalmology·G W ZaidmanCatherine C Furey
May 1, 2007·Ophthalmology·James V AquavellaGregory J McCormick
Dec 12, 2012·Veterinary Ophthalmology·Hassan HamoudiSteffen Heegaard
Nov 15, 2014·Archives of Disease in Childhood. Fetal and Neonatal Edition·Michael J Wan, Deborah K VanderVeen
Jun 10, 2010·Korean Journal of Ophthalmology : KJO·Ki Cheol ChangJin Hak Lee
Nov 29, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Gregorio A MillettGary Marks
Nov 11, 2015·Expert Reviews in Molecular Medicine·Gary Hin-Fai YamJodhbir S Mehta
Apr 5, 2017·Japanese Journal of Ophthalmology·Antonio Di ZazzoMichele Fortunato
Feb 7, 2018·Cornea·Yu Qiang Soh, Jodhbir S Mehta
Oct 15, 2014·The American Orthoptic Journal·Anagha MedsingeK K Nischal
Apr 30, 2017·Der Pathologe·M C Herwig-CarlA M Müller
Jun 27, 2008·Cornea·Rashmi KapurDeepak P Edward
Apr 14, 2020·Journal of Ophthalmology·Wen-Si ChenLan-Xiang Hu
Feb 8, 2011·European Journal of Ophthalmology·Chrysanthi BasdekidouGeorges Caputo
Feb 9, 2021·Molecular Genetics and Metabolism Reports·Bharesh K ChauhanK K Nischal

Related Concepts

Corneal Opacity
Ophthalmology Specialty
Prescribing Patterns, Physician
Patient Referral
Retrospective Studies
Keratoplasty, Penetrating

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.