Congenital heart disease in the newborn requiring early intervention

Korean journal of pediatrics
Sin Weon Yun

Abstract

Although antenatal diagnostic technique has considerably improved, precise detection and proper management of the neonate with congenital heart disease (CHD) is always a great concern to pediatricians. Congenital cardiac malformations vary from benign to serious conditions such as complete transposition of the great arteries (TGA), critical pulmonary and aortic valvular stenosis/atresia, hypoplastic left heart syndrome (HLHS), obstructed total anomalous pulmonary venous return (TAPVR), which the baby needs immediate diagnosis and management for survival. Unfortunately, these life threatening heart diseases may not have obvious evidence early after birth, most of the clinical and physical findings are nonspecific and vague, which makes the diagnosis difficult. High index of suspicion and astute acumen are essential to decision making. When patent ductus arteriosus (PDA) is opened widely, many serious malformations may not be noticed easily in the early life, but would progress as severe acidosis/shock/cyanosis or even death as PDA constricts after few hours to days. Ductus dependent congenital cardiac lesions can be divided into the ductus dependent systemic or pulmonary disease, but physiologically quite different from each oth...Continue Reading

References

Feb 1, 1986·The American Journal of Cardiology·A E LinR G Williams
Mar 23, 1999·The Annals of Thoracic Surgery·J S TweddellS B Litwin
Apr 28, 1999·Pediatric Clinics of North America·R T Fedderly
Apr 28, 1999·Pediatric Clinics of North America·J D Waldman, J A Wernly
Apr 26, 2001·Archives of Disease in Childhood. Fetal and Neonatal Edition·D J Penny, L S Shekerdemian
Jul 26, 2002·Indian Journal of Pediatrics·Usha S Krishnan
Mar 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·George M HoffmanStuart Berger
Sep 7, 2004·Journal of Perinatal Medicine·Gyula TálosiSándor Túri
Jun 27, 2006·Child and Adolescent Psychiatric Clinics of North America·Kristen M Powaski
Jan 30, 2007·The Journal of Thoracic and Cardiovascular Surgery·Jia LiGlen S Van Arsdell
Oct 24, 2007·Emergency Medicine Clinics of North America·Linton Yee
Oct 8, 2008·Archives of Pediatrics & Adolescent Medicine·Ruey-Kang R ChangSandra Rodriguez
Oct 15, 2008·Orphanet Journal of Rare Diseases·Paula Martins, Eduardo Castela
Aug 18, 2009·Lancet·David J BarronWilliam J Brawn
Dec 8, 2010·Circulation·Anna N SealeUNKNOWN British Congenital Cardiac Association

❮ Previous
Next ❯

Citations

Jun 1, 2014·Pediatric Annals·Jarrett LinderPaula Williams
Sep 24, 2015·International Journal of Legal Medicine·Krzysztof Jerzy WoźniakEwa Rzepecka-Woźniak
May 20, 2014·Archives of Disease in Childhood. Education and Practice Edition·A J JonesA N Seale
Mar 20, 2018·Archivos de cardiología de México·María Guadalupe Jiménez-CarbajalClaudia Paola Fernández Luna
Sep 9, 2019·Journal of Perinatal Medicine·Alaa EbrashyMohamed Momtaz
Mar 13, 2018·Case Reports in Pediatrics·Rachel LeveneMichael Keenaghan
Jun 18, 2017·World Journal of Pediatrics : WJP·Katarzyna BogusiakPiotr Arkuszewski
Jun 6, 2018·Frontiers in Pediatrics·Yogen Singh, Cécile Tissot
Dec 15, 2020·Annals of Pediatric Cardiology·Mohd Nizam Mat BahEmieliyuza Yusnita Alias

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.