Congenital Infantile Fibrosarcoma in the Premature Infant

Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses
Taryn M EdwardsTamara M Meeker

Abstract

Congenital infantile fibrosarcoma (CIF) is rare and represents less than 1% of all childhood cancers. It is a tumor that originates in the connective fibrous tissue found at the ends of long bones and then spreads to other surrounding soft tissues. These lesions are typically large, grow rapidly, and can often be mistaken for teratomas. Diagnosis is confirmed by pathology, where cellular proliferation of fibroblasts occurs. Imaging is an important part of the diagnosis, which includes the use of magnetic resonance imaging and/or computed tomography scan. Although surgical resection is the primary treatment, chemotherapeutic agents may be used as adjuvant therapy. To describe modalities for accurate diagnosis and treatment of CIF. PubMed was searched using terms "congenital infantile fibrosarcoma" and "infantile fibrosarcoma." Eleven relevant, English language articles were identified and utilized in the preparation of this case presentation. Complications addressed in this case presentation are prenatal diagnostic challenges, pharmacologic interventions in the setting of prematurity, immunosuppression, and acute liver and renal failure. Pharmacologic treatments will include chemotherapy agents, antimicrobial agents, as well as ...Continue Reading

References

Sep 19, 2003·The New England Journal of Medicine·Gregory L KearnsRalph E Kauffman
Oct 4, 2011·Seminars in Ultrasound, CT, and MR·Rebecca Stein-Wexler
Nov 15, 2011·Journal of Pediatric Surgery·Ahmed H Al-Salem
Apr 14, 2012·Journal of Pediatric Surgery·Motoi MukaiKazuo Chijiiwa
Apr 27, 2013·Paediatric Anaesthesia·Karel AllegaertJohn van den Anker
Mar 29, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·S G FarmakisM J Siegel
Apr 8, 2014·Pediatric Radiology·Kelly E AinsworthGlenn Taylor
Sep 30, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·S IslamJ A Kulhanjian
Nov 26, 2014·Annals of Plastic Surgery·Melissa KanackAmanda Gosman
Mar 15, 2015·Indian Journal of Surgical Oncology·Rajinder KumarM C Sharma
Feb 6, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Daniel OrbachAndrea Ferrari
May 15, 2016·Seminars in Oncology·Veronica J ShiJennifer N Choi
Jul 6, 2016·Pediatric Emergency Care·Stephen AlerhandAlex Koyfman
Dec 22, 2016·International Journal of Molecular Sciences·Victoria HarrisAlan Cooper

❮ Previous
Next ❯

Citations

Apr 4, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Emilio J Inarejos ClementeOscar M Navarro

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

© 2022 Meta ULC. All rights reserved