PMID: 9631396Jun 19, 1998Paper

Congenital myopathies with inclusion bodies: a brief review

Neuromuscular Disorders : NMD
H H Goebel

Abstract

Based on morphological abnormalities, congenital myopathies can be classified into several categories: (1) enzyme histochemically abnormal appearance without structural pathology, e.g., congenital fibre type disproportion or congenital fibre type uniformity; (2) abnormally placed nuclei, e.g. myotubular and centronuclear myopathies; (3) disruption of normal intrinsic structures, largely sarcomeres, e.g. central cores and minicores; (4) abnormal inclusions within muscle fibres. Several such inclusions are derived from pre-existing structures, most notably rods or nemaline bodies. Other derivatives of Z-band material are cytoplasmic bodies and possibly related inclusions as spheroid bodies, sarcoplasmic bodies or Mallory body-like inclusions. These inclusions share accumulation of desmin, the muscle fibre-specific intermediate filament, and of other proteins, some of them physiological, but others quite abnormal. Inclusions without identified precursors are fingerprint bodies, reducing bodies, cylindrical spirals, and Zebra bodies. Experimental models and tissue culture reproduction are necessary to further clarify significance of these inclusions in congenital myopathy pathology.

References

Apr 1, 1975·Journal of the Neurological Sciences·B D Lake, J Wilson
Oct 1, 1976·Archives of Neurology·M FardeauS Derambure
Jul 1, 1979·Muscle & Nerve·S CarpenterC Melmed
Jan 1, 1978·Muscle & Nerve·H H GoebelA D Merritt
Jan 1, 1975·Acta Neuropathologica·F M Tomé, M Fardeau
Jan 1, 1992·Neuromuscular Disorders : NMD·A PrelleG Scarlato
Jan 1, 1991·Neuromuscular Disorders : NMD·A L TaratutoG Sevlever
Oct 1, 1987·Journal of Child Neurology·M G ReyesA Bouffard
Apr 25, 1988·FEBS Letters·L RappaportM Fardeau
Jun 1, 1971·Neurology·P A CancillaC M Pearson
Aug 1, 1972·Neurology·M H Brooke, H E Neville
May 1, 1981·Neuropediatrics·H H GoebelH G Lenard
Mar 1, 1983·Muscle & Nerve·A FidzianskaU Langenbeck
Mar 1, 1983·Neurology·R RohkammF Jerusalem
Mar 1, 1983·Archives of Neurology·S J Oh, M J Danon
Jan 1, 1981·Virchows Archiv. A, Pathological Anatomy and Histology·M E StoeckelK Weber
Jan 1, 1980·Virchows Archiv. A, Pathological Anatomy and Histology·A PorteA Batzenschlager
Jun 1, 1980·Annals of Neurology·K E BoveF Samaha
May 1, 1994·Neuromuscular Disorders : NMD·R J BarohnJ R Mendell
Jul 1, 1995·Journal of the Neurological Sciences·A FidziańskaH H Goebel
Sep 1, 1993·Neuromuscular Disorders : NMD·A CaronB Lechevalier
Jun 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·J VajsarE G Murphy
May 1, 1996·Journal of Neuropathology and Experimental Neurology·S NakanoN A Busis
Sep 1, 1996·Journal of the Neurological Sciences·A PrelleG Scarlato
Jan 1, 1997·Journal of Child Neurology·H H GoebelM Gaude
Jan 1, 1997·Neuromuscular Disorders : NMD·H H Goebel, I Warlo
May 1, 1997·Neuromuscular Disorders : NMD·H H GoebelI Warlo
Jun 3, 1998·Neuromuscular Disorders : NMD·J A LobrinusJ Bogousslavsky

❮ Previous
Next ❯

Citations

Apr 30, 2008·Histochemistry and Cell Biology·P StrnadH Denk
Jun 20, 2001·Acta Physiologica Scandinavica·L Carlsson, L E Thornell
Aug 22, 2006·Brain & Development·Maki OhsawaIchizo Nishino
Aug 13, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Pavel StrnadM Bishr Omary
Aug 13, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Shinichiro HanadaM Bishr Omary
Sep 26, 2000·Molecular Genetics and Metabolism·H H Goebel, I Warlo
Sep 20, 2001·Current Opinion in Neurology·N TubridyB Eymard
Jan 9, 2015·American Journal of Physiology. Cell Physiology·Karla P García-PelagioRobert J Bloch
Aug 17, 2005·Arquivos de neuro-psiquiatria·Rosana Hermínia ScolaLineu Cesar Werneck

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Cell Biology
Ikuo NakamichiM Bishr Omary
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Masaru HaradaM Bishr Omary
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire
M Cadrin, M G Martinoli
© 2022 Meta ULC. All rights reserved